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Causes

By Mayo Clinic staff

All food allergies are caused by an immune system malfunction. Your immune system identifies certain soy proteins as harmful, triggering the production of immunoglobulin E (IgE) antibodies to neutralize the soy protein (allergen). The next time you come in contact with soy, these IgE antibodies recognize it and signal your immune system to release histamine and other chemicals into your bloodstream.

Histamine and other body chemicals cause a range of allergic signs and symptoms. Histamine is partly responsible for most allergic responses, including runny nose, itchy eyes, dry throat, rashes and hives, nausea, diarrhea, labored breathing, and even anaphylactic shock.

Researchers have identified at least 15 possible allergens in soy protein, which comes from soybeans. Exactly how soy protein causes an allergic reaction is still not clear.

References
  1. Atkins D. Food allergy: Diagnosis and management. Primary Care: Clinics in Office Practice. 2008;35:119.
  2. Sampson HA, et al. Adverse reactions to foods. In: Adkinson NF, et al. Middleton's Allergy: Principles and Practice. 7th ed. St. Louis, Mo.: Mosby; 2008. http://www.mdconsult.com/das/book/body/129272040-4/824208035/1806/69.html#4-u1.0-B978-0-323-05659-5..00065-6--s0290_2209. Accessed March 31, 2009.
  3. Schwartz LB. Systemic anaphylaxis, food allergy and insect sting allergy. In: Goldman L, et al., eds. Goldman: Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/129272040-5/824210429/1492/978.html#4-u1.0-B978-1-4160-2805-5..50279-2_12464. Accessed March 31, 2009.
  4. Keet CA, et al. Food allergy and anaphylaxis. Immunology and Allergy Clinics of North America. 2007;27:193.
  5. Soy allergy. Asthma and Allergy Foundation of America. https://www.aafa.org/display.cfm?id=9&sub=20&cont=522. Accessed March 31, 2009.
  6. Sicherer SH, et al. Maternal and infant diets for prevention of allergic diseases: Understanding menu changes in 2008. Journal of Allergy and Clinical Immunology. 2008;122:29.
  7. Rank MA (expert opinion). Mayo Clinic, Rochester, Minn. April 6, 2009.

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May 23, 2009

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