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Causes

By Mayo Clinic staff

All food allergies are caused by an immune system reaction. Your immune system identifies certain soy proteins as harmful, triggering the production of immunoglobulin E (IgE) antibodies to the soy protein (allergen). The next time you come in contact with soy, these IgE antibodies recognize it and signal your immune system to release histamine and other chemicals into your bloodstream.

Histamine and other body chemicals cause a range of allergic signs and symptoms. Histamine is partly responsible for most allergic responses, including runny nose, itchy eyes, dry throat, rashes and hives, nausea, diarrhea, difficulty breathing, and even anaphylactic shock.

References
  1. Savage JH, et al. The natural history of soy allergy. Journal of Allergy and Clinical Immunology. 2010;6:125.
  2. Atkins D. Food allergy: Diagnosis and management. Primary Care: Clinics in Office Practice. 2008;35:119.
  3. Sicherer SH. Food allergens: Overview of clinical features and cross-reactivity. http://www.uptodate.com/home/index.html. Accessed Feb. 8, 2011.
  4. Keet CA, et al. Food allergy and anaphylaxis. Immunology and Allergy Clinics of North America. 2007;27:193.
  5. Ballmer-Weber BK, et al. Soy allergy in perspective. Current Opinion in Allergy and Clinical Immunology. 2008;8:270.
  6. Soy allergy. Asthma and Allergy Foundation of America. http://www.aafa.org/print.cfm?id=9&sub=20&cont=522. Accessed Feb. 8, 2011.
  7. Thygarahan A, et al. American Academy of Pediatrics recommendations on the effects of early nutritional interventions on the development of atopic disease. Current Opinion in Pediatrics. 2008;20:698.
DS00970 May 20, 2011

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