What you can expect
By Mayo Clinic staffBefore sperm donation, you'll likely be asked to abstain from ejaculation — either through sex or masturbation — for two to five days.
During the procedure
Sperm donation is typically done at a sperm bank. You'll provide a semen sample in a sterile cup through masturbation in a private room.
After the procedure
After you provide a sperm donation, the sample will be frozen (cryopreserved) and kept in quarantine for at least 180 days. Then you'll be tested again for infectious diseases, such as HIV.
If all of your test results come back negative, your frozen sample will be thawed and sperm quantity, quality and movement will be evaluated again. Sperm samples from some men are more susceptible to damage during the freezing process than are others. Damage caused by the freezing process can also differ among samples from the same donor.
If your sperm meet the quality standards, you'll be selected as a donor.
Keep in mind that most sperm banks limit the number of children your sperm can be used to conceive. However, specific guidelines and limits vary.
If you test positive for any medical conditions, you'll be notified and referred to treatment and counseling.
- What you should know - Reproductive tissue donation. U.S. Food and Drug Administration. http://www.fda.gov/BiologicsBloodVaccines/SafetyAvailability/TissueSafety/ucm232876.htm?utm_campaign=Google2&utm_source=fdaSearch&utm_medium=website&utm_term=sperm donation&utm_content=5. Accessed June 8, 2012.
- Infertility fact sheet. Office on Women's Health. http://www.womenshealth.gov/publications/our-publications/fact-sheet/infertility.cfm. Accessed June 8, 2012.
- Optimizing male fertility. American Society for Reproductive Medicine. http://www.asrm.org/uploadedFiles/ASRM_Content/Resources/Patient_Resources/Fact_Sheets_and_Info_Booklets/Optimizing%20male%20fertility%20FINAL%204-23-12.pdf. Accessed June 7, 2012.
- Third party reproduction: A guide for patients. American Society for Reproductive Medicine. http://www.asrm.org/uploadedFiles/ASRM_Content/Resources/Patient_Resources/Fact_Sheets_and_Info_Booklets/thirdparty.pdf. Accessed June 7, 2012.
- Intrauterine insemination. American Society for Reproductive Medicine. http://www.asrm.org/awards/detail.aspx?id=8576&terms=(+%40Publish_To+Both+Sites+or+%40Publish_To+ASRM+Only+)+and+third+party+reproduction. Accessed June 7, 2012.
- Treating infertility. American College of Obstetricians and Gynecologists. http://www.acog.org/publications/patient_education/bp137.cfm. Accessed June 7, 2012.
- Ginsburg ES, et al. Donor insemination. http://www.uptodate.com/index. Accessed June 7, 2012.
- Practice Committee of the American Society for Reproductive Medicine, et al. 2008 Guidelines for Gamete andEmbryo Donation: A Practice Committee report. Fertility and Sterility. 2008;90:S30.
- Wang C, et al. Treatment of male infertility. http://www.uptodate.com/index. Accessed June 7, 2012.
- Ginsburg ES. Procedure for intrauterine insemination. http://www.uptodate.com/index. Accessed June 7, 2012.
- Cooper TG, et al. World Health Organization reference values for human semen characteristics. World Health Organization. http://www.who.int/reproductivehealth/publications/infertility/human_repro_upd/en. Accessed June 11, 2012.


Find Mayo Clinic on