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Risk factors

By Mayo Clinic staff

Living With Cancer

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Spinal cord tumors are more common in people who have:

  • Neurofibromatosis 2. In this hereditary disorder, noncancerous tumors develop on or near the nerves related to hearing, which may lead to progressive hearing loss in one or both ears. Some people with neurofibromatosis 2 also develop tumors in the spinal cord.
  • Von Hippel-Lindau disease. This rare, multisystem disorder is associated with noncancerous blood vessel tumors (hemangioblastomas) in the brain, retina and spinal cord and with other types of tumors in the kidneys or adrenal glands.
  • A compromised immune system. Spinal cord lymphomas — cancers that affect lymphocytes, a type of immune cell — are more common in people whose immune systems are compromised by medications or disease.
  • A prior history of cancer. Any type of cancer can travel to the spine, but the cancers that may be more likely to affect the spine include breast, lung, prostate and multiple myeloma.
References
  1. Donthineni R. Diagnosis and staging of spine tumors. Orthopedic Clinics of North America. 2009;40:1.
  2. Brain and spinal tumors: Hope through research. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/brainandspinaltumors/detail_brainandspinaltumors.htm#43233060. Accessed Aug. 28, 2011.
  3. DeAngelis LM. Tumors of the central nervous system and intracranial hypertension and hypotension. In: Goldman L, et al., eds. Cecil Medicine. 24th ed. Philadelphia, Pa.: Saunders Elsevier; 2011. http://www.mdconsult.com/das/book/body/191371208-2/0/1492/0.html#.  Accessed Sept. 2, 2011
  4. Spinal cord tumors. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/print/sec17/ch236/ch236g.html. Accessed Aug. 31, 2011.
  5. Smith ML, et al. Neurosurgery. In: Brunicardi FC, et al., eds. Schwartz's Principles of Surgery. 9th ed. New York, N.Y.: The McGraw-Hill Companies; 2010. http://www.accessmedicine.com/content.aspx?aID=5020575. Accessed Sept. 1, 2011.
  6. Gurd DP. Back pain in the young athlete. Sports Medicine Arthroscopy Review. 2011;19:7
  7. Detailed guide: Brain and spinal cord tumors in adults. American Cancer Society. http://www.cancer.org/acs/groups/cid/documents/webcontent/003088-pdf.pdf. Accessed Aug. 28, 2011.
  8. Sundaresen N. Primary malignant tumors of the spine. Orthopedic Clinics of North America. 2009;40:21.
  9. Chamberlain MC, et al. Adult primary intradural spinal cord tumors: A review. Current Neurology and Neuroscience Report. 2011;11:320.
  10. Sachdev S, et al. Stereotactic radiosurgery yields long-term control for benign intradural, extramedullary spinal tumors.  Neurosurgery. 2011;69:533.
  11. Sagar SM. Acupuncture as an evidence-based option for symptom control in cancer patients. Current Treatment Options in Oncology. 2008;9:117.
  12. Moynihan TJ (expert opinion). Mayo Clinic, Rochester, Minn. Sept. 2, 2011.
DS00594 Oct. 21, 2011

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