Definition
By Mayo Clinic staffSquamous cell carcinoma is a common form of skin cancer that develops in the thin, flat squamous cells that make up the outer layer of the skin.
Squamous cell carcinoma is usually not life-threatening, though it can be aggressive in some cases. Untreated, squamous cell carcinoma can grow large or spread to other parts of your body, causing serious complications.
Most squamous cell carcinomas result from prolonged exposure to ultraviolet (UV) radiation, either from sunlight or from tanning beds or lamps. Avoiding UV light helps reduce your risk of squamous cell carcinoma and other forms of skin cancer.
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- Gibson LE (expert opinion). Mayo Clinic, Rochester, Minn. Feb. 21, 2013.


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