Squamous cell carcinoma


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Definition

By Mayo Clinic staff

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Photo of a squamous cell carcinoma on the ear and on the lip 
Squamous cell carcinoma

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Squamous cell carcinoma is a common form of skin cancer that develops in the thin, flat squamous cells that make up the outer layer of the skin.

Squamous cell carcinoma is usually not life-threatening, though it can be aggressive in some cases. Untreated, squamous cell carcinoma can grow large or spread to other parts of your body, causing serious complications.

Most squamous cell carcinomas result from prolonged exposure to ultraviolet (UV) radiation, either from sunlight or from tanning beds or lamps. Avoiding UV light helps reduce your risk of squamous cell carcinoma and other forms of skin cancer.

References
  1. Habif TP. Clinical Dermatology: A Color Guide to Diagnosis and Therapy. 5th ed. Edinburgh, U.K.; New York, N.Y.: Mosby Elsevier; 2010. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-7234-3541-9..X0001-6--TOP&isbn=978-0-7234-3541-9&uniqId=230100505-57. Accessed Feb. 12, 2013.
  2. Goldsmith LA, et al., eds. Fitzpatrick's Dermatology in General Medicine. 8th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=740.  Accessed Feb. 12, 2013.
  3. Skin cancer treatment (PDQ). National Cancer Institute. http://cancer.gov/cancertopics/pdq/treatment/skin/Patient. Accessed Feb. 12, 2013.
  4. Skin cancer prevention. Centers for Disease Control and Prevention. http://www.cdc.gov/cancer/skin/basic_info/prevention.htm. Accessed Feb. 19, 2013.
  5. Gibson LE (expert opinion). Mayo Clinic, Rochester, Minn. Feb. 21, 2013.
DS00924 May 1, 2013

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