ComplicationsBy Mayo Clinic staff
Untreated squamous cell carcinoma can destroy nearby healthy tissue, spread to the lymph nodes or other organs, and may be fatal, although this is uncommon.
The risk of aggressive squamous cell carcinoma may be increased in cases where the cancer:
- Is particularly large or deep
- Involves the mucous membranes, such as the lips
- Occurs in a person with weakened immune systems, such as someone who takes anti-rejection medications after an organ transplant
- Habif TP. Clinical Dermatology: A Color Guide to Diagnosis and Therapy. 5th ed. Edinburgh, U.K.; New York, N.Y.: Mosby Elsevier; 2010. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-7234-3541-9..X0001-6--TOP&isbn=978-0-7234-3541-9&uniqId=230100505-57. Accessed Feb. 12, 2013.
- Goldsmith LA, et al., eds. Fitzpatrick's Dermatology in General Medicine. 8th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=740. Accessed Feb. 12, 2013.
- Skin cancer treatment (PDQ). National Cancer Institute. http://cancer.gov/cancertopics/pdq/treatment/skin/Patient. Accessed Feb. 12, 2013.
- Skin cancer prevention. Centers for Disease Control and Prevention. http://www.cdc.gov/cancer/skin/basic_info/prevention.htm. Accessed Feb. 19, 2013.
- Gibson LE (expert opinion). Mayo Clinic, Rochester, Minn. Feb. 21, 2013.