Squamous cell carcinoma

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Complications

By Mayo Clinic staff

When treated early, squamous cell carcinomas generally cause no problems. Although this is uncommon, untreated squamous cell carcinoma can destroy healthy tissue around the tumor, spread to the lymph nodes or other organs, and occasionally prove fatal.

People who have had organ transplants or have chronic lymphocytic leukemia or HIV/AIDS are far more likely to have an aggressive form of squamous cell carcinoma than are people who are otherwise healthy.

Squamous cell carcinomas with the highest risk of complications include:

  • Tumors on the lips and ears. Squamous cell carcinomas in these locations are more likely to spread to other sites or recur after treatment.
  • Large tumors. Squamous cell carcinomas measuring about 3/4 inch (about 2 centimeters) or more — are also more likely to spread than smaller tumors are.
  • Deep tumors. Squamous cell carcinomas that have deeply invaded muscle, cartilage or bone are more likely to recur.
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References
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April 4, 2009

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