Definition
By Mayo Clinic staffStaph infections are caused by staphylococcus bacteria, a type of germ commonly found on the skin or in the nose of even healthy individuals. Most of the time, these bacteria cause no problems or result in relatively minor skin infections.
But staph infections can turn deadly if the bacteria invade deeper into your body, entering your bloodstream, joints, bones, lungs or heart.
In the past, a lethal staph infection might have occurred in a person who was hospitalized or had a chronic illness or weakened immune system. Now, a growing number of otherwise healthy people are developing life-threatening staph infections. And many staph infections no longer respond to common antibiotics.
- Ogle JW, et al. Infections: Bacterial & spirochetal. In: Hay Jr. WW, et al. Current Diagnosis & Treatment: Pediatrics. 20th ed. New York, N.Y.: McGraw-Hill Medical; 2011. http://www.accessmedicine.com/content.aspx?aID=6590808. Accessed May 5, 2011.
- Que Y, et al. Staphylococcus aureus (including staphylococcal toxic shock). In: Mandell GL, et al. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2010. http://www.mdconsult.com/books/linkTo?type=bookPage&isbn=978-0-443-06839-3&eid=4-u1.0-B978-0-443-06839-3..00195-8. Accessed May 5, 2011.
- Endocarditis. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/endo/endo_all.html. Accessed May 5, 2011.
- Lowy FD. Staphylococcal infections. In: Fauci AS, et al. Harrison's Online. 17th ed. New York, N.Y.: The McGraw-Hill Companies; 2008. http://www.accessmedicine.com/content.aspx?aID=2870999. Accessed May 9, 2011.
- Archer GL. Staphylococcal infections. In: Goldman L. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/books/linkTo?type=bookPage&isbn=978-1-4160-2805-5&eid=4-u1.0-B978-1-4160-2805-5..50315-3 Accessed May 9, 2011.
- Baddour LM. Cellulitis and erysipelas. http://www.uptodate.com/home/index.html. Accessed May 9, 2011.
- Staphylococcal food poisoning. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dbmd/diseaseinfo/staphylococcus_food_g.htm. Accessed May 9, 2011.
- Fowler VG, et al. Complications of staphylococcus aureus bacteremia. http://www.uptodate.com/home/index.html. Accessed May 9, 2011.
- Kirkland EB, et al. Methicillin-resistant Staphylococcus aureus and athletes. Journal of the American Academy of Dermatology. 2008;59:494.
- Sepsis and septic shock. The Merck Manuals: Home Edition for Patients and Caregivers. http://www.merckmanuals.com/home/sec17/ch191/ch191c.html. Accessed May 9, 2011.
- Staphylococcus aureus (SA): Antibiotic resistance (general). National Institute of Allergy and Infectious Disease. http://science.education.nih.gov/supplements/nih1/diseases/activities/activity5_vrsa-database.htm. Accessed May 9, 2011.
- Personal prevention of MRSA skin infections. Centers for Disease Control and Prevention. http://www.cdc.gov/mrsa/prevent/personal.html. Accessed May 9, 2011.
- Liu C, et al. Clinical practice guidelines by the Infectious Diseases Society of America for the treatment of methicillin-resistant staphylococcus aureus infections in adults and children. Clinical Infectious Diseases. 2011;52:1.


Find Mayo Clinic on