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Prevention
By Mayo Clinic staffIt's difficult to prevent an initial attack of Stevens-Johnson syndrome because you don't know what will trigger it. However, if you had Stevens-Johnson syndrome once, and your doctor determined that it was caused by medication, be sure to avoid that medication and others in the same class to prevent another attack. If the herpes virus caused your reaction, you may need to take daily antiviral medications to prevent a recurrence.
A recurrence of Stevens-Johnson syndrome is usually more severe than the first episode and, in many cases, it can be fatal.
- Nirken MH, et al. Stevens-Johnson syndrome and toxic epidermal necrolysis: Clinical manifestations; pathogenesis; and diagnosis. http://www.uptodate.com/home/index.html. Accessed Dec. 13, 2010.
- High WA, et al. Stevens-Johnson syndrome and toxic epidermal necrolysis: Management, prognosis, and long-term sequelae. http://www.uptodate.com/home/index.html. Accessed Dec. 13, 2010.
- Evans J. Topical treatment protocol for Stevens-Johnson syndrome and toxic epidermal necrolysis. Journal of Wound Ostomy & Continence Nursing. 2009;36:509.
- Hazin R, et al. Derm diagnoses you can't afford to miss. The Journal of Family Practice. 2009;58:298.
- Knowles S, et al. Clinical risk management of Stevens-Johnson syndrome/toxic epidermal necrolysis spectrum. Dermatologic Therapy. 2009;22:441.
- Ward KE, et al. Severe adverse skin reactions to nonsteroidal anti-inflammatory drugs: A review of the literature. American Journal of Health-System Pharmacy. 2010;67:206.
- Usatine RP, et al. Dermatologic emergencies. American Family Physician. 2010;82:773.
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