ComplicationsBy Mayo Clinic staff
Although strep throat itself isn't dangerous, it may lead to serious complications — sometimes even with treatment.
Spread of infection
Strep bacteria may spread, causing infection in your:
- Middle ear
Strep infection may lead to other inflammatory illnesses, including:
- Scarlet fever, an illness characterized by a rash
- Inflammation of the kidney (poststreptococcal glomerulonephritis)
- Rheumatic fever, a serious condition that can affect the heart, joints, nervous system and skin
Researchers are investigating a possible link between strep infection and a rare condition called Pediatric autoimmune neuropsychiatric disorder associated with group A streptococci (PANDAS). PANDAS is a term used to describe certain children whose symptoms of neuropsychiatric conditions, such as obsessive compulsive disorder or tic disorders, are exacerbated by strep infection.
- Sore throat. Centers for Disease Control and Prevention. http://www.cdc.gov/getsmart/antibiotic-use/uri/sore-throat.html. Accessed Sept. 17, 2012.
- Pichichero ME. Complications of streptococcal tonsillopharyngitis. http://www.uptodate.com/index. Accessed Sept. 17, 2012.
- Sore throats. American Academy of Otolaryngology — Head and Neck Surgery. http://www.entnet.org/HealthInformation/soreThroats.cfm. Accessed Sept. 17, 2012.
- Alter SJ, et al. Common childhood bacterial infections. Current Problems in Pediatric and Adolescent Health Care. 2011;41:256.
- Strep throat. National Institute of Allergy and Infectious Diseases. http://www.niaid.nih.gov/topics/strepThroat/Pages/Default.aspx. Accessed Sept. 18, 2012.
- Kliegman RM, et al. Nelson Textbook of Pediatrics. 19th ed. Philadelphia, Pa.: Saunders Elsevier; 2011. http://www.mdconsult.com/das/book/body/208746819-6/0/1608/0.html. Accessed Sept. 20, 2012.
- Bope ET, et al. Conn's Current Therapy. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-1-4377-0986-5..C2009-0-38984-9--TOP&isbn=978-1-4377-0986-5&about=true&uniqId=236797353-5. Accessed Sept. 19, 2012.
- Group A streptococcal (GAS) disease. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dbmd/diseaseinfo/groupastreptococcal_g.htm. Accessed Sept. 19, 2012.
- Sore throat? Know when to call the doctor. American Osteopathic Association. http://www.osteopathic.org/osteopathic-health/about-your-health/health-conditions-library/general-health/Pages/sore-throat.aspx. Accessed Sept. 20, 2012.
- Pichichero ME. PANDAS: Pediatric autoimmune neuropsychiatric disorder associated with group A streptococci. http://www.uptodate.com/index. Accessed Sept. 17, 2012.
- Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 Update by the Infectious Diseases Society of America.Infectious Disease Society of America. Arlington, Va. http://www.idsociety.org/uploadedFiles/IDSA/Guidelines-Patient_Care/PDF_Library/2012%20Strep%20Guideline.pdf. Accessed Sept. 17, 2012.
- Pichichero ME. Treatment and prevention of streptococcal tonsillopharyngitis. http://www.uptodate.com/index. Accessed Sept. 17, 2012.
- Steckelberg JM (expert opinion). Mayo Clinic, Rochester, Minn. Oct. 2, 2012.