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Complications

By Mayo Clinic staff

Although strep throat itself isn't dangerous, it may lead to serious complications — sometimes even with treatment.

Spread of infection
Strep bacteria may spread, causing infection in your:

  • Tonsils
  • Sinuses
  • Skin
  • Blood
  • Middle ear

Inflammatory reactions
Strep infection may lead to other inflammatory illnesses, including:

  • Scarlet fever, an illness characterized by a rash
  • Inflammation of the kidney (poststreptococcal glomerulonephritis)
  • Rheumatic fever, a serious condition that can affect the heart, joints, nervous system and skin

The risk of developing severe complications from strep throat is low in the United States.

References
  1. Strep throat. National Institute of Allergy and Infectious Disease. http://www.niaid.nih.gov/topics/strepThroat/Pages/default.aspx. Accessed April 22, 2010.
  2. Giannoni CM. Streptococcal pharyngitis. In: Bope ET, et al. Conn's Current Therapy 2010. 61st ed. Philadelphia, Pa.: Saunders Elsevier; 2009. http://www.mdconsult.com/book/player/book.do?method=display&type=bookPage&decorator=header&eid=4-u1.0-B978-1-4160-6642-2..00003-X--sc0070&uniq=195595841&isbn=978-1-4160-6642-2. Accessed April 22, 2010.
  3. Fort GG. Pharyngitis/tonsillitis. In: Ferri FF. Ferri's Clinical Advisor 2010. St. Louis, Mo.: Mosby; 2009. http://www.mdconsult.com/das/book/body/197105845-8/0/2088/496.html?tocnode=58133576&fromURL=496.html#4-u1.0-B978-0-323-05609-0..00025-3--sc0140_10202. Accessed April 22, 2010.
  4. Choby B. Diagnosis and treatment of streptococcal pharyngitis. American Family Physician. 2009;79:383.
  5. Hayden GF, et al. Acute pharyngitis. In: Kliegman RM, et al. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/197105845-9/0/1608/897.html?tocnode=54482109&fromURL=897.html#4-u1.0-B978-1-4160-2450-7..50380-7_7372. Accessed April 22, 2010.
  6. Fleisher GR. Evaluation of sore throat in children. http://www.uptodate.com/home/index.html. Accessed April 22, 2010.
  7. Fort GG. Rheumatic fever. In: Ferri FF. Ferri's Clinical Advisor 2010. St. Louis, Mo.: Mosby; 2009. http://www.mdconsult.com/das/book/body/195595841-8/984459939/2088/572.html#4-u1.0-B978-0-323-05609-0..00027-7--s2315_11750. Accessed April 22, 2010.
  8. Hoecker JL (expert opinion). Mayo Clinic, Rochester, Minn. April 30, 2010.
DS00260 June 26, 2010

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