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Risk factors

By Mayo Clinic staff

Living With Cancer

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Factors that may increase your risk of testicular cancer include:

  • An undescended testicle (cryptorchidism). The testes form in the abdominal area during fetal development and usually descend into the scrotum before birth. Men who have a testicle that never descended are at greater risk of testicular cancer in either testicle than are men whose testicles descended normally. The risk remains even if the testicle has been surgically relocated to the scrotum. Still, the majority of men who develop testicular cancer don't have a history of undescended testicles.
  • Abnormal testicle development. Conditions that cause testicles to develop abnormally, such as Klinefelter's syndrome, may increase your risk of testicular cancer.
  • Family history. If family members have had testicular cancer, you may have an increased risk.
  • Age. Testicular cancer affects teens and younger men, particularly those between ages 15 and 34. However, it can occur at any age.
  • Race. Testicular cancer is more common in white men than in black men.
References
  1. Ryan CJ, et al. Testicular cancer. In: Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone; 2008:1713.
  2. Testicular cancer. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed Aug. 22, 2011.
  3. Richie JP, et al. Neoplasms of the testis. In: Wein AJ, et al. Campbell-Walsh Urology. 9th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/208746819-6/0/1445/0.html. Accessed Aug. 22, 2011.
  4. Testicular self examination (TSE). American Urological Association Foundation. http://www.urologyhealth.org/urology/index.cfm?article=101. Accessed Aug. 22, 2011.
  5. Ilic D, et al. Screening for testicular cancer. Cochrane Database of Systematic Reviews. 2011;CD007853. http://www2.cochrane.org/reviews. Accessed Aug. 22, 2011.
DS00046 Oct. 15, 2011

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