• image.alt
  • With Mayo Clinic gynecologist and obstetrician

    Mary M. Gallenberg, M.D.

    read biography

Free

E-Newsletters

Subscribe to receive the latest updates on health topics. About our newsletters

  • Housecall
  • Alzheimer's caregiving
  • Living with cancer

Question

Testosterone therapy in women: Does it boost sex drive?

Does testosterone therapy help increase sex drive in menopausal women? When should this be considered? What are the pros and cons?

Answer

from Mary M. Gallenberg, M.D.

Research shows that the hormone testosterone does effectively boost sex drive — as well as remedy other sexual problems — in certain women with sexual dysfunction. But whether or not to use testosterone therapy presents a dilemma for women and their doctors. The long-term safety of testosterone therapy for women is unknown. Some experts recommend testosterone therapy; others believe more research is needed.

Testosterone therapy usually is prescribed only for women who have sufficient estrogen levels and not for women who are postmenopausal and can't or choose not to take estrogen. Testosterone therapy might be appropriate if:

  • You have reduced sex drive, depression and fatigue after surgically-induced menopause and estrogen therapy hasn't been effective in relieving your symptoms
  • You're postmenopausal, you're taking estrogen therapy and you have a decreased sex drive with no other identifiable causes

Testosterone therapy isn't appropriate for postmenopausal women who have a history of breast or uterine cancer or those who have cardiovascular or liver disease.

Testosterone therapy for women usually comes in the form of a cream, gel or patch, but sometimes it's prescribed as a pill. However, no commonly prescribed testosterone preparations have been approved by the Food and Drug Administration for use in women. If testosterone is prescribed, it's for off-label use.

Although testosterone contributes to healthy sexual function in women, other factors play a larger role in postmenopausal sexual dysfunction. These factors include decreased estrogen levels, vaginal dryness, medication side effects, chronic health conditions, loss of a spouse or partner, lack of emotional intimacy, conflict, stress, or mood concerns.

Next question
Bleeding after menopause: Is it normal?
References
  1. The North American Menopause Society. The role of testosterone therapy in postmenopausal women: Position statement of The North American Menopause Society. Menopause. 2005;12:497.
  2. Androgen therapy in women: An Endocrine Society clinical practice guideline. Chevy Chase, Md.: The Endocrine Society. http://jcem.endojournals.org/cgi/content/abstract/91/10/3697. Accessed June 3, 2010.
  3. Schwenkhagen A, et al. Role of testosterone in the treatment of hypoactive sexual desire disorder. Maturitas. 2009;63:152.
  4. Shifren JL. Sexual dysfunction in women: Management. http://www.uptodate.com/home/index.html. Accessed June 3, 2010.
  5. Krapf JM, et al. The role of testosterone in the management of hypoactive sexual desire disorder in postmenopausal women. Maturitas. 2009;63:213.
  6. Panzer C, et al. Testosterone replacement therapy in naturally and surgically menopausal women. The Journal of Sexual Medicine. 2009;6:8.
AN01390 July 22, 2010

© 1998-2012 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

Print Share Reprints

Advertisement


Text Size: smaller largerlarger