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Definition

By Mayo Clinic staff

Tetanus is a serious bacterial disease that affects your nervous system, leading to painful muscle contractions, particularly of your jaw and neck muscles. Tetanus can interfere with your ability to breathe and, ultimately, threaten your life. Tetanus is commonly known as "lockjaw."

Thanks to the tetanus vaccine, cases of tetanus are rare in the United States and the developed world. The incidence of tetanus is much higher in less-developed countries. Around a million cases occur worldwide each year.

Tetanus can be treated, but not always effectively. Fatality is highest in individuals who haven't been immunized and in older adults with inadequate immunization — wherever they may live. In countries with low vaccine rates, infants also are at high risk of severe illness and death.

References
  1. Tetanus: Questions and answers. Immunization Action Coalition. http://www.immunize.org/catg.d/p4220.pdf. Accessed Aug. 18, 2010.
  2. Facts about tetanus for adults. National Foundation for Infectious Diseases. http://www.nfid.org/pdf/factsheets/tetanusadult.pdf.
  3. Sexton DJ. Tetanus. http://www.uptodate.com/home/index.html. Accessed Aug. 18, 2010.
  4. Kretsinger K, et al. Tetanus. In: Roush SW, et al. Manual for the Surveillance of Vaccine-Preventable Diseases. 4th ed. Atlanta, Ga.: Centers for Disease Control and Prevention; 2008. http://www.cdc.gov/vaccines/pubs/surv-manual/chpt16-tetanus.htm. Accessed Aug. 18, 2010.
  5. Tetanus. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/print/sec14/ch178/ch178i.html. Accessed Aug. 20, 2010.
  6. Diphtheria, tetanus & pertussis vaccines: What you need to know. Centers for Disease Control and Prevention. http://www.cdc.gov/vaccines/pubs/vis/downloads/vis-dtap.pdf. Accessed Aug. 20, 2010.
  7. Tetanus, diphtheria (Td) or tetanus, diphtheria, pertussis (Tdap) vaccine: What you need to know. Centers for Disease Control and Prevention. http://www.cdc.gov/vaccines/pubs/vis/downloads/vis-td-tdap.pdf. Accessed Aug. 20, 2010.
  8. Emergency wound care after a natural disaster. Centers for Disease Control and Prevention. http://www.bt.cdc.gov/disasters/woundcare.asp. Accessed Aug. 20, 2010.
DS00227 Sept. 18, 2010

© 1998-2013 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

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