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Causes
By Mayo Clinic staffThe bacteria that cause tetanus, Clostridium tetani, are found in soil, dust and animal feces. When they enter a deep flesh wound, spores of the bacteria may produce a powerful toxin, tetanospasmin, which actively impairs your motor neurons, nerves that control your muscles. The effect of the toxin on your nerves can cause muscle stiffness and spasms — the major signs of tetanus.
- Tetanus: Questions and answers. Immunization Action Coalition. http://www.immunize.org/catg.d/p4220.pdf. Accessed Aug. 18, 2010.
- Facts about tetanus for adults. National Foundation for Infectious Diseases. http://www.nfid.org/pdf/factsheets/tetanusadult.pdf.
- Sexton DJ. Tetanus. http://www.uptodate.com/home/index.html. Accessed Aug. 18, 2010.
- Kretsinger K, et al. Tetanus. In: Roush SW, et al. Manual for the Surveillance of Vaccine-Preventable Diseases. 4th ed. Atlanta, Ga.: Centers for Disease Control and Prevention; 2008. http://www.cdc.gov/vaccines/pubs/surv-manual/chpt16-tetanus.htm. Accessed Aug. 18, 2010.
- Tetanus. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/print/sec14/ch178/ch178i.html. Accessed Aug. 20, 2010.
- Diphtheria, tetanus & pertussis vaccines: What you need to know. Centers for Disease Control and Prevention. http://www.cdc.gov/vaccines/pubs/vis/downloads/vis-dtap.pdf. Accessed Aug. 20, 2010.
- Tetanus, diphtheria (Td) or tetanus, diphtheria, pertussis (Tdap) vaccine: What you need to know. Centers for Disease Control and Prevention. http://www.cdc.gov/vaccines/pubs/vis/downloads/vis-td-tdap.pdf. Accessed Aug. 20, 2010.
- Emergency wound care after a natural disaster. Centers for Disease Control and Prevention. http://www.bt.cdc.gov/disasters/woundcare.asp. Accessed Aug. 20, 2010.
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