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Complications

By Mayo Clinic staff

Once tetanus toxin has bonded to your nerve endings it is impossible to remove. Complete recovery from a tetanus infection requires the growth of new nerve endings and can take up to several months.

Complications of tetanus infection may include:

  • Disability. Treatment for tetanus typically involves the use of powerful sedatives to control muscle spasms. Prolonged immobility due to the use of these drugs can lead to permanent disability. In infants, tetanus infections may cause lasting brain damage, ranging from minor mental deficits to cerebral palsy.
  • Death. Severe tetanus-induced (tetanic) muscle spasms can interfere with your breathing, causing periods in which you can't breathe at all. Respiratory failure is the most common cause of death. Lack of oxygen may also induce cardiac arrest and death. Pneumonia is another cause of death.
References
  1. Tetanus: Questions and answers. Immunization Action Coalition. http://www.immunize.org/catg.d/p4220.pdf. Accessed Aug. 18, 2010.
  2. Facts about tetanus for adults. National Foundation for Infectious Diseases. http://www.nfid.org/pdf/factsheets/tetanusadult.pdf.
  3. Sexton DJ. Tetanus. http://www.uptodate.com/home/index.html. Accessed Aug. 18, 2010.
  4. Kretsinger K, et al. Tetanus. In: Roush SW, et al. Manual for the Surveillance of Vaccine-Preventable Diseases. 4th ed. Atlanta, Ga.: Centers for Disease Control and Prevention; 2008. http://www.cdc.gov/vaccines/pubs/surv-manual/chpt16-tetanus.htm. Accessed Aug. 18, 2010.
  5. Tetanus. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/print/sec14/ch178/ch178i.html. Accessed Aug. 20, 2010.
  6. Diphtheria, tetanus & pertussis vaccines: What you need to know. Centers for Disease Control and Prevention. http://www.cdc.gov/vaccines/pubs/vis/downloads/vis-dtap.pdf. Accessed Aug. 20, 2010.
  7. Tetanus, diphtheria (Td) or tetanus, diphtheria, pertussis (Tdap) vaccine: What you need to know. Centers for Disease Control and Prevention. http://www.cdc.gov/vaccines/pubs/vis/downloads/vis-td-tdap.pdf. Accessed Aug. 20, 2010.
  8. Emergency wound care after a natural disaster. Centers for Disease Control and Prevention. http://www.bt.cdc.gov/disasters/woundcare.asp. Accessed Aug. 20, 2010.
DS00227 Sept. 18, 2010

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