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Treatments and drugs
By Mayo Clinic staffTreatment of thrombocytosis is directed at the underlying cause. If the cause is a recent surgery or an injury that caused significant blood loss, your elevated platelet count may be short-lived. If the cause is a chronic infection or an inflammatory disease, your platelet count may remain high until the condition is brought under control.
Some procedures, such as removal of your spleen, may cause lifelong thrombocytosis. In that case, your doctor may prescribe low-dose aspirin to help prevent blood-clotting incidents, although they are rare with reactive thrombocytosis.
