Thumb arthritis

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Causes

By Mayo Clinic staff

The exact cause of thumb arthritis, as with osteoarthritis in general, isn't known. Researchers suspect that it's a combination of factors, including being overweight, the aging process, joint injury or stress, heredity, muscle weakness, and "cumulative load" to the joint. Cumulative load refers to repetitive use of your joint, such as in assembly line work.

Made up of the small bone at the base of your thumb (trapezium), the first bone of your thumb (first metacarpal) and the wrist's scaphotrapezio-trapezoidal joint, the basal joint allows your thumb its wide range of motion and allows your hand to pinch, grip and grasp objects.

In a normal basal joint, cartilage covers the ends of the bones — acting as a cushion and allowing bones to glide smoothly against each other. With thumb arthritis, the cartilage that covers the ends of the bones deteriorates and its smooth surface roughens. The bones then rub against each other, resulting in friction and joint damage.

Your body goes to work repairing the damage, but the repairs may be inadequate, resulting instead in growth of new bone along the sides of the existing bone (bone spurs), which can produce noticeable lumps on your thumb joint.

References
  1. Swigart CR. Arthritis of the base of the thumb. Current Reviews in Musculoskeletal Medicine. 2008;1:142.
  2. Arthritis of the thumb. American Academy of Orthopaedic Surgeons. http://orthoinfo.aaos.org/topic.cfm?topic=A00210. Accessed Feb. 2, 2010.
  3. Deune EG, et al. The patient with hand, wrist, or elbow pain. In: Current Rheumatology Diagnosis & Treatment. 2nd ed. New York, N.Y.: McGraw-Hill Medical; 2007. http://www.accessmedicine.com/content.aspx?aid=2729561. Accessed Feb. 2, 2010.
  4. Dias R, et al. Basal thumb arthritis. Postgraduate Medical Journal. 2007;83:40.
  5. 5. Arthritis: Base of the thumb. American Society for Surgery of the Hand. http://www.assh.org/PUBLIC/HANDCONDITIONS/Pages/ArthritisBaseofthe.aspx. Accessed Feb. 2, 2010.
  6. Osteoarthritis. National Institute of Arthritis and Musculoskeletal and Skin Diseases. http://www.niams.nih.gov/Health_Info/Osteoarthritis/default.asp. Accessed Feb. 3, 2010.
  7. What is arthroscopy? American Academy of Orthopaedic Surgeons. http://orthoinfo.aaos.org/topic.cfm?topic=A00109. Accessed Feb. 3, 2010.
  8. Looking after your joints when you have arthritis. Arthritis Research Campaign. http://www.arc.org.uk/arthinfo/patpubs/6055/6055.asp. Accessed Feb. 3, 2010.
  9. Wajon A, et al. Surgery for thumb (trapeziometacarpal joint) osteoarthritis. Cochrane Database of Systematic Reviews. 2009:CD004631.
DS00703 March 9, 2010

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