Thunderclap headaches

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Causes

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Some thunderclap headaches appear as a result of:

  • No obvious physical reason

In other cases, potentially life-threatening conditions may be responsible, including:

  • Bleeding between the brain and membranes covering the brain
  • A rupture of a blood vessel in the brain
  • A tear in the lining of an artery (for example, carotid or vertebral artery) that supplies blood to the brain
  • Leaking of cerebrospinal fluid which when present is usually due to a tear of the covering around a nerve root in the spine
  • A tumor in the third ventricle of the brain that blocks the flow of cerebrospinal fluid
  • Death of tissue or bleeding in the pituitary gland
  • A blood clot in the brain
  • Severe elevation in blood pressure
  • Infection such as meningitis or encephalitis
References
  1. Olesen J, et al. The international classification of headache disorders. International Headache Society. http://ihs-classification.org/en/02_klassifikation/02_teil1/04.06.00_other.html. Accessed Oct. 19, 2011.
  2. Approach to the patient with headache. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/neurologic_disorders/headache/approach_to_the_patient_with_headache.html. Accessed Oct. 23, 2011.
  3. Goadsby PJ, et al. Headache. In: Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies, Inc. 2011. http://www.accessmedicine.com/content.aspx?aID=9094791. Accessed Oct. 23, 2011.
  4. Headache: Hope through research. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/headache/detail_headache.htm. Accessed Oct. 23, 2011.
  5. DuPont SA, et al. Thunderclap headache and normal computed tomographic results: Value of cerebrospinal fluid analysis. Mayo Clinic Proceedings. 2008;83:1326.
  6. Savitz SI, et al. Thunderclap headache with normal CT and lumbar puncture: Further investigations are unnecessary: For. Stroke. 2008;39:1392.
  7. Tarshish S, et al. Teaching case presentation: Primary thunderclap headache. Headache. 2009;49:1249.
  8. Mistry N, et al. Thunderclap headache. Practical Neurology. 2009;9:294.
  9. Neurological diagnostic tests and procedures. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/misc/diagnostic_tests.htm. Accessed Oct. 23, 2011.
  10. Headache Classification Subcommittee of the International Headache Society. The international classification of headache disorders: 2nd ed. Cephalalgia. 2004;24(suppl):9.
DS00644 Feb. 8, 2012

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