- With Mayo Clinic endocrinologist
Todd B. Nippoldt, M.D.
read biographyclose windowBiography of
Todd B. Nippoldt, M.D.
Todd B. Nippoldt, M.D.
Dr. Todd Nippoldt is a board-certified specialist in internal medicine and endocrinology and metabolism. He has special expertise in the area of hormone disorders affecting the pituitary and adrenal glands as well as the testes and ovaries. He has been a member of the Mayo Clinic staff since 1988.
Dr. Nippoldt is a consultant in the Division of Endocrinology, Metabolism and Nutrition and works with patients who have disorders of the hormone-producing glands. Common disorders include diabetes, thyroid problems, osteoporosis and elevated cholesterol levels.
He also is involved in andrology, the study of male hormonal disorders, male infertility and sexual dysfunction and is an assistant professor of medicine at Mayo Clinic College of Medicine.
Dr. Nippoldt, a St. Paul, Minn., native, has also contributed to "Mayo Clinic Health Letter," a Mayo Clinic CD-ROM and the "Mayo Clinic Family Health Book." He is a fellow in the American College of Physicians and a member of the American Society of Reproductive Medicine, the American Society of Andrology, The Endocrine Society, The Pituitary Society and the American Association of Clinical Endocrinologists.
"I have found that those patients who have gone to the Internet and obtained accurate medical information come to their appointment with me very well informed, and the discussions regarding the evaluation and management of their condition are very productive and satisfying," he says.
"The key, however, is obtaining accurate medical information. As a medical editor for MayoClinic.com, I hope to be able to ensure that accurate, relevant and up-to-date information is available for patients and their families."
Mayo Clinic Health Manager
Get free personalized health guidance for you and your family.
Get Started
About our e-newsletters
- Free e-newsletters
- Mayo Clinic expertise
- We do not share your e-mail address
Housecall, our weekly general-interest e-newsletter, keeps you up to date on a wide variety of health topics with timely, reliable, practical information, recipes, blogs, questions and answers with Mayo Clinic experts and more. Our biweekly topic-specific e-newsletters also include blogs, questions and answers with Mayo Clinic experts, and other useful information that will help you manage your health.
Housecall Archives
Mayo Clinic Housecall
Stay up to date on the latest health information.
What you get
- Free weekly e-newsletter
- Mayo Clinic expertise
- Recipes, tools and other helpful information
- We do not share your e-mail address
Question
Thyroid peroxidase antibody test: What is it?
What is a thyroid peroxidase antibody test? Does it diagnose thyroid disease?
Answer
from Todd B. Nippoldt, M.D.
If you've been diagnosed with thyroid disease, your doctor may recommend a thyroid peroxidase (TPO) antibody test — in addition to other thyroid tests — to help determine the cause. TPO, an enzyme normally found in the thyroid gland, plays an important role in the production of thyroid hormones. A thyroid peroxidase test detects antibodies against TPO in the blood.
The presence of thyroid peroxidase antibodies in your blood suggests that the cause of thyroid disease is due to an autoimmune disorder such as Hashimoto's disease or Graves' disease. In autoimmune disorders, your immune system makes antibodies that mistakenly attack normal tissue. Antibodies that attack the thyroid gland cause inflammation and impaired function of the thyroid.
Your doctor may also order a thyroid peroxidase test if you are pregnant and have a thyroid disease such as Hashimoto's disease or Graves' disease. In such cases, the thyroid peroxidase test can help determine whether your baby is at risk of thyroid disease.
Some people without thyroid disease may have TPO antibodies. However, the presence of thyroid peroxidase antibodies may increase the risk of future thyroid disorders. If you have normal thyroid function with TPO antibodies, your doctor may recommend periodic checkups to watch for future thyroid problems.
