Toxic hepatitis

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Prevention

By Mayo Clinic staff

Because it's not possible to know how you'll react to a particular medication, toxic hepatitis can't always be prevented. But you may reduce your risk of liver problems if you:

  • Limit medications. Take prescription and nonprescription drugs only when absolutely necessary. Investigate nondrug options for common problems such as high blood pressure, high cholesterol and arthritis pain.
  • Take medications only as directed. Follow the directions exactly for any drug you take. Don't exceed the recommended amount, even if your symptoms don't seem to improve. Because the effects of over-the-counter pain relievers sometimes wear off quickly, it's easy to take too much.
  • Be cautious with herbs and supplements. Don't assume that a natural product won't cause harm. Discuss the benefits and risks with your doctor before taking herbs and supplements.
  • Don't mix alcohol and drugs. Alcohol and medications are a bad combination. If you're taking acetaminophen, don't drink alcohol. Ask your doctor or pharmacist about the interaction between alcohol and other prescription and nonprescription drugs you use.
  • Take precautions with chemicals. If you work with or use hazardous chemicals, take all necessary precautions to protect yourself from exposure. If you do come in contact with a harmful substance, follow the guidelines in your workplace, or call your local emergency services or the poison control center for help.
  • Keep medications and chemicals away from children. Keep all medications and vitamin supplements away from children and in childproof containers so that children can't accidentally swallow them.
References
  1. Teoh NC, et al. Liver disease caused by drugs. In: Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 9th ed. Philadelphia, Pa.: Saunders Elsevier; 2010. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-1-4160-6189-2..X0001-7--TOP&isbn=978-1-4160-6189-2&about=true&uniqId=229999237-13. Accessed Nov. 11, 2010.
  2. Lewis JH. Liver disease caused by anesthetics, toxins and herbal preparations. In: Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 9th ed. Philadelphia, Pa.: Saunders Elsevier; 2010. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-1-4160-6189-2..X0001-7--TOP&isbn=978-1-4160-6189-2&about=true&uniqId=229999237-13. Accessed Nov. 11, 2010.
  3. Jones AL, et al. Hepatic toxicology. In: Shannon MW, et al. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose. 4th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-7216-0693-4..50002-5&isbn=978-0-7216-0693-4&uniqId=226391226-4. Accessed Nov. 12, 2010.
  4. Guss DA, et al. Disorders of the liver and biliary tract. In: Marx JA, et al. Rosen's Emergency Medicine. 7th ed. Philadelphia, Pa.: Mosby; 2009. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-0-323-05472-0..X0001-1--TOP&isbn=978-0-323-05472-0&about=true&uniqId=230052158-6. Accessed Nov. 11, 2010.
  5. Rodgers GC, et al. Poisonings. In: Kliegman RM. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/208746819-6/0/1608/0.html. Accessed Nov. 17, 2010.
DS00811 Dec. 17, 2010

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