Toxic shock syndrome


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Definition

By Mayo Clinic staff

Toxic shock syndrome is a rare, life-threatening complication of bacterial infection. It has been historically associated with the use of superabsorbent tampons and occasionally with the use of contraceptive sponges.

Often toxic shock syndrome results from toxins produced by Staphylococcus aureus (staph) bacteria, but the condition may also be caused by toxins produced by group A streptococcus (strep) bacteria.

While the syndrome can occur in menstruating women, it can also affect men, children and postmenopausal women. Risk factors for toxic shock syndrome include skin wounds and surgery.

Signs and symptoms of toxic shock syndrome develop suddenly, and the disease can be fatal. You can take steps to reduce your risk of toxic shock syndrome.

References
  1. Cosgrove SE. Staphylococcal toxic shock syndrome. http://www.uptodate.com/home/index.html. Accessed April 7, 2011.
  2. Eschenbach DA. Pelvic and sexually transmitted infections. In: Gibbs RS, et al. Danforth's Obstetrics and Gynecology. 10th ed. Philadelphia, Pa.: Wolters Kluwer Health Lippincott Williams & Wilkins; 2008. http://www.danforthsobgyn.com. Accessed April 11, 2011.
  3. Que Y, et al. Staphylococcus aureus (including staphylococcal toxic shock). In: Mandell JE, et al. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2010. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-443-06839-3..X0001-X--TOP&isbn=978-0-443-06839-3&uniqId=230100505-57. Accessed April 11, 2011.
  4. Eckert LO, et al. Infections of the lower genital tract: Vulva, vagina, cervix, toxic shock syndrome, HIV infections. In: Katz VL, et al. Comprehensive Gynecology. 5th ed. Philadelphia, Pa.: Mosby Elsevier; 2007. http://www.mdconsult.com/das/book/body/208746819-4/0/1524/0.html. Accessed April 11, 2011.
  5. Menstruation and the menstrual cycle. The National Women's Health Information Center. http://www.womenshealth.gov/faq/menstruation.cfm. Accessed April 11, 2011.
DS00221 May 7, 2011

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