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Complications

By Mayo Clinic staff

If you have a strong immune system, you're not likely to experience any complications of toxoplasmosis, although otherwise healthy people sometimes develop eye infections.

But if your immune system is compromised, especially as a result of HIV/AIDS, toxoplasmosis can lead to seizures and life-threatening illnesses such as encephalitis — a serious brain infection. In people living with AIDS, untreated encephalitis resulting from toxoplasmosis is fatal. Relapse is a constant concern for immunocompromised people with toxoplasmosis.

Children with congenital toxoplasmosis may develop disabling complications, including hearing loss, blindness and mental retardation.

References
  1. Toxoplasmosis fact sheet. Centers for Disease Control and Prevention. http://www.cdc.gov/toxoplasmosis/factsheet.html. Accessed May 5, 2009.
  2. Martin-Rabada P, et al. Blood and tissue protozoa. In: Cohen J, et al. Infectious Diseases. 2nd ed. New York, N.Y.: Mosby; 2004. http://www.mdconsult.com/das/book/body/135708454-2/0/1209/737.html?tocnode=49359306&fromURL=737.html#4-u1.0-B0-323-02407-6..50247-6--cesec17_8111. Accessed May 4, 2009.
  3. Kasper LH. Toxoplasma infections. In: Fauci AS, et al. Harrison's Principles of Internal Medicine. 17th ed. New York, N.Y.: McGraw-Hill Medical; 2008. http://www.accessmedicine.com/content.aspx?aid=2896423. Accessed May 4, 2009.
  4. McLeod R, et al. Toxoplasmosis (toxoplasma gondii). In: Kleigman RM, et al. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/das/book/body/135783748-2/0/1608/732.html?tocnode=54480801&fromURL=732.html#4-u1.0-B978-1-4160-2450-7..50289-9_6064. Accessed May 4, 2009.
  5. Toxoplasmosis. March of Dimes. http://www.marchofdimes.com/professionals/14332_1228.asp. Accessed May 6, 2009.
  6. Centers for Disease Control and Prevention, et al. Preventing congenital toxoplasmosis. MMWR Recommendations and Reports. 2000;49:57. http://www.cdc.gov/mmwr/preview/mmwrhtml/rr4902a5.htm. Accessed May 8, 2009.
  7. You can prevent toxo. Centers for Disease Control and Prevention. http://www.cdc.gov/hiv/resources/brochures/toxo.htm. Accessed May 5, 2009.
  8. Montoya JG, et al. Diagnosis and management of toxoplasmosis. Clinics in Perinatology. 2005;32:705.

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June 27, 2009

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