Transcranial magnetic stimulation

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Risks

By Mayo Clinic staff

Transcranial magnetic stimulation (TMS) is the least invasive of the brain-stimulation procedures used for depression. Unlike vagus nerve stimulation or deep brain stimulation, TMS doesn't require surgery or implantation of electrodes. And, unlike electroconvulsive therapy (ECT), it doesn't cause seizures or require complete sedation with anesthesia. However, TMS does have some risks and can cause some side effects.

Common side effects
TMS often causes minor short-term side effects. These side effects are generally mild and typically improve after the first week or two of treatment. They can include:

  • Headache
  • Scalp discomfort at the site of stimulation
  • Tingling, spasms or twitching of facial muscles
  • Lightheadedness
  • Discomfort from noise during treatment

Uncommon side effects
Serious side effects are rare. They can include:

  • Seizures
  • Mania, particularly in people with bipolar disorder
  • Hearing loss due to inadequate ear protection during treatment

More study is needed to determine whether TMS may have any long-term side effects.

References
  1. Brain stimulation therapies. National Institute of Mental Health. http://www.nimh.nih.gov/health/topics/brain-stimulation-therapies/brain-stimulation-therapies.shtml. Accessed Oct. 18, 2012.
  2. Hales RE, et al. The American Psychiatric Publishing Textbook of Psychiatry. 5th ed. Washington, D.C.: American Psychiatric Publishing; 2008. http://www.psychiatryonline.com/resourceToc.aspx?resourceID=5. Accessed Oct. 22, 2012.
  3. Holtzheimer PE. Unipolar depression in adults: Treatment with transcranial magnetic stimulation (TMS). http://www.uptodate.com/index. Accessed Oct. 22, 2012.
  4. Rasmussen KG. Some considerations in choosing electroconvulsive therapy versus transcranial magnetic stimulation for depression. Journal of ECT. 2011;27:51.
  5. Cusin C, et al. Somatic therapies for treatment-resistant depression: ECT, TMS, VNS, DBS. Biology of Mood & Anxiety Disorders. 2012;2:14.
  6. Transcranial magnetic stimulation (TMS or rTMS). National Alliance on Mental Illness. http://www.nami.org/Content/ContentGroups/Helpline1/Transcranial_Magnetic_Stimulation_(rTMS).htm. Accessed Oct. 24, 2012.
  7. Kung S (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 1, 2012.
MY00185 Nov. 20, 2012

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