Transient ischemic attack (TIA)

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Causes

By Mayo Clinic staff

A transient ischemic attack has the same origins as that of an ischemic stroke, the most common type of stroke. In an ischemic stroke, a clot blocks the blood supply to part of your brain. In a transient ischemic attack, unlike a stroke, the blockage is brief and there is no permanent damage.

The underlying cause of a TIA often is a buildup of cholesterol-containing fatty deposits called plaques (atherosclerosis) in an artery or one of its branches that supply oxygen and nutrients to your brain. Plaques can decrease the blood flow through an artery or lead to the development of a clot. Other causes include a blood clot moving to your brain from another part of your body, most commonly from your heart.

References
  1. Transient ischemic attack. American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=4781. Accessed Dec. 30, 2008.
  2. Wu CM, et al. Early risk of stroke after transient ischemic attack: A systematic review and meta-analysis. Archives of Internal Medicine. 2007;167:2417.
  3. Stroke risk factors. American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=4716. Accessed Dec. 30, 2008.
  4. Sacco RL, et al. Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack. Stroke. 2006;37:577.
  5. NINDS transient ischemic attack information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/tia/tia.htm. Accessed Dec. 31, 2008.
  6. Lewandowski CA, et al. Transient ischemic attack: Definitions and clinical presentations. Annals of Emergency Medicine. 2008;52:S7.
  7. Ischemic stroke. http://www.merck.com/mmpe/sec16/ch211/ch211b.html?qt=transient%20ischemic%20attack&alt=sh#sec16-ch211-ch211b-446. Accessed Dec. 31, 2008.
  8. Sudlow C. Dipyridamole with aspirin is better than aspirin alone in preventing vascular events after ischaemic stroke or TIA. British Medical Journal. 2007;334:901.

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March 3, 2009

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