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Risk factors
By Mayo Clinic staffAlthough the exact cause of transposition of the great arteries is unknown, several factors may increase the risk of a baby being born with this condition. These include:
- A mother who had rubella (German measles) or another viral illness during pregnancy
- A parent who had transposition of the great arteries or another congenital heart defect
- Poor nutrition during pregnancy
- Excessive alcohol consumption during pregnancy
- A mother older than 40
- A mother who has diabetes
- Down syndrome in the baby, which increases the risk of transposition of the great arteries and other congenital heart defects
