Trigeminal neuralgia

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Causes

By Mayo Clinic staff

In trigeminal neuralgia, also called tic douloureux, the trigeminal nerve's function is disrupted. Usually, the problem is contact between a normal blood vessel — in this case, an artery or a vein — and the trigeminal nerve, at the base of your brain. This contact puts pressure on the nerve and causes it to malfunction.

Trigeminal neuralgia can occur as a result of aging, or it can be related to multiple sclerosis or a similar disorder that damages the myelin sheath protecting certain nerves. Less commonly, trigeminal neuralgia can be caused by a tumor compressing the trigeminal nerve. In other cases, a cause can't be found.

Triggers
A variety of triggers may set off the pain of trigeminal neuralgia, including:

  • Shaving
  • Stroking your face
  • Eating
  • Drinking
  • Brushing your teeth
  • Talking
  • Putting on makeup
  • Encountering a breeze
  • Smiling
References
  1. Trigeminal neuralgia fact sheet. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/trigeminal_neuralgia/detail_trigeminal_neuralgia.htm. Accessed Feb. 18, 2010.
  2. Bajwa ZH. Trigeminal neuralgia. http://www.uptodate.com/home/index.html. Accessed Feb. 18, 2010.
  3. Sohur US. Trigeminal neuralgia. In: Ferri FF. Ferri's Clinical Advisor 2010. St. Louis, Mo.: Mosby; 2009. http://www.mdconsult.com/das/book/body/183930156-4/0/2088/674.html#4-u1.0-B978-0-323-05609-0..00029-0--sc0175_13740. Accessed Feb. 18, 2010.
  4. Krafft RM. Trigeminal neuralgia. American Family Physician. 2008;77:1291.
  5. AAN and EFNS guideline on diagnosing and treating trigeminal neuralgia. St. Paul, Minn.: American Academy of Neurology (AAN). http://www.aafp.org/afp/2009/0601/p1001.html. Accessed Feb. 18, 2010.
  6. Young RF. Trigeminal neuralgia. In: Rakel RE, et al. Conn's Current Therapy 2008. 60th ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/book/player/book.do?method=display&type=bookPage&decorator=header&eid=4-u1.0-B978-1-4160-6642-2..00014-4--sc0075&uniq=183930156&isbn=978-1-4160-6642-2&sid=954069268#lpState=open&lpTab=contentsTab&content=4-u1.0-B978-1-4160-6642-2..00014-4--sc0075%3Bfrom%3Dtoc%3Btype%3DbookPage%3Bisbn%3D978-1-4160-6642-2. Accessed Feb. 18, 2010.
  7. Nerve blocks. Radiological Society of North America. http://www.radiologyinfo.org/en/info.cfm?pg=nerveblock#part_nine. Accessed Feb. 18, 2010.
  8. Singla A. Trigeminal neuralgia. In: Frontera WR, et al. Essentials of Physical Medicine and Rehabilitation. 2nd ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/das/book/body/184337872-8/955217002/1678/94.html#4-u1.0-B978-1-4160-4007-1..50092-4--cesec12_1483. Accessed Feb. 18, 2010.
  9. Swanson JW (expert opinion). Mayo Clinic, Rochester, Minn. March 1, 2010.
DS00446 April 15, 2010

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