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Symptoms
By Mayo Clinic staffTriple X syndrome may not cause any signs or symptoms. If symptoms do appear, they may include:
- Tall stature
- Vertical skinfolds that may cover the inner corners of the eyes (epicanthal folds)
- Delayed development of speech and language skills
- Weak muscle tone (hypotonia)
- Curved pinky fingers (clinodactyly)
- Behavior and mental health problems
- Premature ovarian failure or ovary abnormalities
- Constipation or abdominal pains
When to see a doctor
See your daughter's doctor if you have any concerns about your daughter's developmental progress. Your doctor can help determine what may be the cause and suggest appropriate action.
References
- Triple X syndrome. U.S. National Library of Medicine's Genetics Home Reference. http://ghr.nlm.nih.gov/condition/triple-x-syndrome. Accessed Sept. 9, 2012.
- 47 XXX syndrome. Genetics and Rare Diseases Information Center. http://rarediseases.info.nih.gov/GARD/Condition/5672/47_XXX_syndrome.aspx. Accessed Sept. 9, 2012.
- Afshun A. Triple X syndrome. Journal of the Pakistan Medical Association. 2012;62:392.
- Otter M, et al. Triple X syndrome: A review of the literature. European Journal of Human Genetics. 2010;18:265.
- Chromosome abnormalities. National Human Genome Research Institute. http://www.genome.gov/11508982#6. Accessed Sept. 10, 2012.
- Chromosomal abnormalities. March of Dimes. http://www.marchofdimes.com/baby/birthdefects_chromosomal.html. Accessed Sept. 11, 2012.
- Tartaglia NR, et al. A review of trisomy X (47,XXX). Orphanet Journal of Rare Diseases. 2010;5:8.
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