Tuberculosis

Mayo Clinic Health Manager

Get free personalized health guidance for you and your family.

Get Started

Free

E-Newsletter

Subscribe to receive the latest updates on health topics. About our newsletters

  • Housecall
  • Alzheimer's caregiving
  • Living with cancer

Prevention

By Mayo Clinic staff

In general, TB is preventable. From a public health standpoint, the best way to control TB is to diagnose and treat people with TB infection before they develop active disease and to take careful precautions with people hospitalized with TB. But there also are measures you can take on your own to help protect yourself and others:

  • Keep your immune system healthy. Eat plenty of healthy foods including fruits and vegetables, get enough sleep, and exercise at least 30 minutes a day most days of the week to keep your immune system in top form.
  • Get tested regularly. Experts advise people who have a high risk of TB to get a skin test once a year. This includes people with HIV or other conditions that weaken the immune system, people who live or work in a prison or nursing home, health care workers, people from countries with high rates of TB, and others in high-risk groups.
  • Consider preventive therapy. If you test positive for latent TB infection, your doctor will likely advise you to take medications to reduce your risk of developing active TB. Vaccination with BCG isn't recommended for general use in the United States, because it isn't very effective in adults and it causes a false-positive result on a Mantoux skin test. But the vaccine is often given to infants in countries where TB is more common. Vaccination can prevent severe TB in children. Researchers are working on developing a more effective TB vaccine.
  • Finish your entire course of medication. This is the most important step you can take to protect yourself and others from TB. When you stop treatment early or skip doses, TB bacteria have a chance to develop mutations that allow them to survive the most potent TB drugs. The resulting drug-resistant strains are much more deadly and difficult to treat.

To help keep your family and friends from getting sick if you have active TB:

  • Stay home. Don't go to work or school or sleep in a room with other people during the first few weeks of treatment for active TB.
  • Ensure adequate ventilation. Open the windows whenever possible to let in fresh air.
  • Cover your mouth. It takes two to three weeks of treatment before you're no longer contagious. During that time, be sure to cover your mouth with a tissue anytime you laugh, sneeze or cough. Put the dirty tissue in a bag, seal it and throw it away. Also, wearing a mask when you're around other people during the first three weeks of treatment may help lessen the risk of transmission.
References
  1. Riley LW. Microbiology and pathogenesis of tuberculosis. http://www.uptodate.com/home/index.html. Accessed Dec. 22, 2008.
  2. Pezzella AT, et al. Surgical aspects of thoracic tuberculosis: A contemporary review - Part 1. Current Problems in Surgery. 2008;45:675.
  3. Summary. In: WHO Report 2008: Global tuberculosis control - Surveillance, planning, financing. World Health Organization. Accessed Dec. 20, 2008. http://www.who.int/tb/publications/global_report/2008/summary/en/index.html.
  4. Bass JB Jr. Patient information: Tuberculosis. http://www.uptodate.com/home/index.html. Accessed Dec. 20, 2008.
  5. Tuberculosis (TB). National Institute of Allergy and Infectious Diseases. http://www3.niaid.nih.gov/topics/tuberculosis/Understanding/WhatIsTB/TBdefinitions.htm. Accessed Dec. 20, 2008.
  6. Tuberculosis. American Lung Association. http://www.lungusa.org/site/apps/nlnet/content3.aspx?c=dvLUK9O0E&b=4294229&ct=5320855. Accessed Dec. 20, 2008.
  7. Tuberculosis fact sheet. American Lung Association. http://www.lungusa.org/site/apps/nlnet/content3.aspx?c=dvLUK9O0E&b=4294229&ct=3052619. Accessed Dec. 20, 2008.
  8. The difference between latent TB infection and active TB disease. Centers for Disease Control and Prevention. http://www.cdc.gov/tb/pubs/tbfactsheets/LTBIandActiveTB.htm. Accessed Dec. 20, 2008.
  9. Tuberculosis (TB): Symptoms. National Institute of Allergy and Infectious Diseases. http://www3.niaid.nih.gov/topics/tuberculosis/Understanding/symptoms.htm. Accessed Dec. 20, 2008.
  10. Tuberculosis: General information. Centers for Disease Control and Prevention. http://www.cdc.gov/tb/pubs/tbfactsheets/tb.htm. Accessed Dec. 20, 2008.
  11. Bass JB Jr. Risk factors for tuberculosis. http://www.uptodate.com/home/index.html. Accessed Dec. 22, 2008.
  12. Maartens G, et al. Tuberculosis. The Lancet. 2007;370:2030.
  13. Key points. In: WHO Report 2008: Global tuberculosis control - Surveillance, planning, financing. World Health Organization. http://www.who.int/tb/publications/global_report/2008/key_points/en/index.html. Accessed Dec. 20, 2008.
  14. Tuberculosis (TB): TB and HIV infection. National Institute of Allergy and Infectious Diseases. http://www3.niaid.nih.gov/topics/tuberculosis/Understanding/tbHIV.htm. Accessed Dec. 20, 2008.
  15. Madariaga MG, et al. Extensively drug-resistant tuberculosis. American Journal of Medicine. 2008;121:835.
  16. Lew W, et al. Initial drug resistance and tuberculosis treatment outcomes: Systematic review and meta-analysis. Annals of Internal Medicine. 2008;149:123.
  17. Fauci AS, et al. Multidrug-resistant and extensively drug-resistant tuberculosis: The National Institute of Allergy and Infectious Diseases research agenda and recommendations for priority research. Journal of Infectious Diseases. 2008;197:1493.
  18. Tuberculosis (TB): TB definitions. National Institute of Allergy and Infectious Diseases. http://www3.niaid.nih.gov/topics/tuberculosis/Understanding/WhatIsTB/TBdefinitions.htm. Accessed Dec. 20, 2008.
  19. Grant A, et al. Clinical review: Managing drug resistant tuberculosis. BMJ. 2008;337:a1110.
  20. Jeong YJ, et al. Pulmonary tuberculosis: Up-to-date imaging and management. American Journal of Radiology. 2008;191:834.
  21. Pediatric tuberculosis fact sheet. American Lung Association. http://www.lungusa.org/site/apps/nlnet/content3.aspx?c=dvLUK9O0E&b=4294229&ct=3052619. Accessed Dec. 20, 2008.
  22. Diagnosis of tuberculosis disease. Centers for Disease Control and Prevention. http://www.cdc.gov/tb/pubs/tbfactsheets/diagnosis.htm. Accessed Dec. 20, 2008.
  23. Catanzaro A. Rapid diagnostic tests for tuberculosis. http://www.uptodate.com/home/index.html. Accessed Dec. 22, 2008.
  24. Tuberculosis skin test fact sheet. American Lung Association. http://www.lungusa.org/site/apps/nl/content3.asp?c=dvLUK9O0E&b=2060731&content_id={E017092A-511A-4871-8EAE-17988C696509}&notoc=1. Accessed Dec. 20, 2008.
  25. Tuberculosis (TB): Diagnosis. National Institute of Allergy and Infectious Diseases. http://www3.niaid.nih.gov/topics/tuberculosis/Understanding/diagnosis.htm. Accessed Dec. 20, 2008.
  26. TB skin test. Lab Tests Online. http://www.labtestsonline.org/understanding/analytes/tb_skin/. Accessed Dec. 22, 2008.
  27. Zhang Y. Advances in the treatment of tuberculosis. Clinical Pharmacology & Therapeutics. 2007;82:595.
  28.  Menzies D, et al. Adverse events with 4 months of rifampin therapy or 9 months of isoniazid therapy for latent tuberculosis infection. Annals of Internal Medicine. 2008;149:689.
  29. HIV and tuberculosis fact sheet. American Lung Association. http://www.lungusa.org/site/apps/nl/content3.asp?c=dvLUK9O0E&b=2060731&content_id=%7bA3132347-3F7C-4ED7-AB4C-34FBEE5B0D4C%7d&notoc=1.
  30. Tuberculosis and pregnancy. Centers for Disease Control and Prevention. http://www.cdc.gov/tb/pubs/tbfactsheets/pregnancy. Accessed Dec. 20, 2008.
  31. Tuberculosis (TB): Prevention. National Institute of Allergy and Infectious Diseases. http://www3.niaid.nih.gov/topics/tuberculosis/Understanding/prevention.htm. Accessed Dec. 20, 2008.

DS00372

Jan. 28, 2009

© 1998-2009 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Reliable tools for healthier lives," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

Print Share Reprints

Text Size: smaller largerlarger