Risk factorsBy Mayo Clinic staff
About one-third of people who have tuberous sclerosis inherit an altered TSC1 or TSC2 gene — the genes associated with tuberous sclerosis — from a parent who has the disease. About two-thirds of people who have tuberous sclerosis have a new mutation in either the TSC1 or TSC2 gene.
If you have tuberous sclerosis, you have a 50 percent chance of passing the condition to your biological children. Severity of the condition may vary. A parent who has mild tuberous sclerosis may have a child who has a more severe form of the disease.
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