Undescended testicle (cryptorchidism)

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Causes

By Mayo Clinic staff

The exact cause of an undescended testicle isn't known. A combination of genetics, maternal health and other environmental factors may disrupt the hormones, physical changes and nerve activity that influence the development of the testicles.

References
  1. Ashley RA, et al. Cryptorchidism: Pathogenesis, diagnosis, treatment and prognosis. Urologic Clinics of North America. 2010;37:183.
  2. Cryptorchidism. In: Ferri FF. Ferri's Clinical Advisor 2010. St. Louis, Mo.: Mosby; 2009. http://www.mdconsult.com/book/player/book.do?method=display&type=bookPage&decorator=header&eid=4-u1.0-B978-0-323-05610-6..00012-3--sc0255&uniq=213947045&isbn=978-0-323-05610-6&sid=1037085104#lpState=open&lpTab=contentsTab&content=4-u1.0-B978-0-323-05610-6..00012-3--s5575%3Bfrom%3Dcontent%3Bisbn%3D978-0-323-05610-6%3Btype%3DbookPage. Accessed Aug. 12, 2010.
  3. Elder JS. Disorders and anomalies of the scrotal contents. In: Kliegman RM, et al. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/213947045-4/1037087645/1608/1246.html#4-u1.0-B978-1-4160-2450-7..50547-8--cesec4_9821. Accessed Aug. 12, 2010.
  4. Cooper CS, et al. Undescended testes (cryptorchidism) in children and adolescents. http://www.uptodate.com/home/index.html. Accessed Aug. 12, 2010.
  5. Braunstein GD. Endocrinology and the life span. In: Kronenberg HM, et al. Williams Textbook of Endocrinology. 11th ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/das/book/body/213947045-6/1037085104/1555/158.html#4-u1.0-B978-1-4160-2911-3..50026-1--cesec117_2351. Accessed Aug. 12, 2010.
  6. Nippoldt TB (expert opinion). Mayo Clinic, Rochester, Minn. Aug. 15, 2010.
DS00845 Oct. 14, 2010

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