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By Mayo Clinic staffAlthough vaginal hysterectomy is generally safe, any surgery has risks. These include blood loss or clots, infection, or reaction to anesthesia. Surgical risks are higher in women who are obese or who have diabetes or high blood pressure.
The location of the uterus in the pelvis means there is a risk of injury to other pelvic and abdominal organs during vaginal hysterectomy, including the bladder, ureters or bowel. The risk of organ injury is greater if large fibroids, severe endometriosis or cancer obstructs the surgeon's view or otherwise makes the surgery difficult.