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Treatments and drugs

By Mayo Clinic staff

A variety of organisms and conditions can cause vaginitis, so treatment targets the specific cause.

  • Bacterial vaginosis. For this type of vaginitis, your doctor may prescribe metronidazole tablets (Flagyl) that you take by mouth, metronidazole gel (MetroGel) that you apply to your vagina, or clindamycin cream (Cleocin) that you apply to your vagina. Medications are usually used once or twice a day for five to seven days.
  • Yeast infections. Yeast infections usually are treated with an antifungal cream or suppository, such as miconazole (Monistat), clotrimazole (Gyne-Lotrimin) and tioconazole (Vagistat). Yeast infections may also be treated with a prescription oral antifungal medication, such as fluconazole (Diflucan). The advantages of over-the-counter treatment for a yeast infection are convenience, cost and not having to wait to see your doctor. The catch is you may be treating something other than a yeast infection. It's possible to mistake a yeast infection for other types of vaginitis or other conditions that need different treatment. Using the wrong medicine may delay a proper diagnosis and the most appropriate treatment.
  • Trichomoniasis. Your doctor may prescribe metronidazole (Flagyl) or tinidazole (Tindamax) tablets.
  • Thinning of vaginal lining (vaginal atrophy). Estrogen, in the form of vaginal creams, tablets or rings, can effectively treat atrophic vaginitis. This treatment is available by prescription from your doctor.
  • Noninfectious vaginitis. To treat this type of vaginitis, you need to pinpoint the source of the irritation and avoid it. Possible sources include new soap, laundry detergent, sanitary napkins or tampons.
References
  1. Eschenbach DA. Pelvic and sexually transmitted infections. In: Gibb RS, et al. Danforth's Obstetrics and Gynecology. 10th ed. Philadelphia, Pa.: Lippincott Williams & Wilkins; 2008:608.
  2. Centers for Disease Control and Prevention, et al. Sexually transmitted diseases treatment guidelines, 2010. MMWR Recommendations and Reports. 2010;59:1. http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5912a1.htm. Accessed Jan. 4, 2011.
  3. Eckert LO, et al. Infections of the lower genital tract: Vulva, vagina, cervix, toxic shock syndrome, HIV infections. In: Katz VL, et al. Comprehensive Gynecology. 5th ed. Philadelphia, Pa.: Mosby Elsevier; 2007. http://www.mdconsult.com/das/book/body/208746819-4/0/1524/0.html. Accessed Jan. 4, 2011.
  4. Nyirjesy P. Vulvovaginal candidiasis and bacterial vaginosis. Infectious Disease Clinics of North America. 2008;22:637.
  5. Castelo-Branco C, et al. Management of post-menopausal vaginal atrophy and atrophic vaginitis. Maturitas. 2005;52(suppl):S46.
  6. American College of Obstetricians and Gynecologists. Vaginitis. Obstetrics & Gynecology. 2006;107:1195.
DS00255 Feb. 5, 2011

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