Tests and diagnosis
By Mayo Clinic staffValley fever is difficult to diagnose solely on the basis of signs and symptoms, which are usually vague and nonspecific, or on a chest X-ray, which can't distinguish valley fever from other lung diseases. Instead, a definitive diagnosis depends on finding evidence of coccidioides organisms in tissue, blood or other body secretions. For that reason, you're likely to have one or more of the following tests:
- Sputum smear or culture. These tests check a sample of the matter that's discharged while coughing (sputum) for the presence of coccidioides organisms.
- Blood tests. Through a blood test, your doctor can check for antibodies against the fungus that causes valley fever.
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- Steckelberg JM (expert opinion). Mayo Clinic, Rochester, Minn. April 10, 2012.


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