Mayo Clinic Health Manager

Get free personalized health guidance for you and your family.

Get Started

Free

E-Newsletter

Subscribe to receive the latest updates on health topics. About our newsletters

  • Housecall
  • Alzheimer's caregiving
  • Living with cancer

Causes

By Mayo Clinic staff

Vascular dementia is most often caused by either a:

  • Complete blockage of blood vessels in the brain. The complete blockage of an artery in the brain usually causes a stroke (infarction), but some blockages don't produce stroke symptoms. These "silent brain infarctions" increase a person's risk of vascular dementia. The risk increases with the number of infarctions experienced over time. One variety of vascular dementia is called multi-infarct dementia. Heart disease and irregular heart rhythms, such as atrial fibrillation, can increase your risk of stroke.
  • Narrowing of the blood vessels in the brain. Vascular dementia also can occur without a complete blockage of an artery. Portions of the brain can be starved for oxygen and food by reduced blood flow from arteries narrowed by vascular disease.

Vascular dementia can also be caused by:

  • Profoundly low blood pressure
  • Brain damage caused by brain hemorrhage
  • Blood vessel damage from such disorders as lupus erythematosus or temporal arteritis
References
  1. Dementia: Hope through research. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/dementias/detail_dementia.htm. Accessed March 14, 2009.
  2. Vascular dementia. Alzheimer's Association. http://www.alz.org/alzheimers_disease_vascular_dementia.asp. Accessed March 14, 2009.
  3. Bird TD, et al. Dementia. In: Fauci AS, et al.: Harrison's Principles of Internal Medicine. 17th ed. New York, N.Y.: McGraw-Hill Medical; 2008. http://www.accessmedicine.com/content.aspx?aID=2904052. Accessed March 11, 2009.
  4. Wright CB. Etiology, clinical manifestations, and diagnosis of vascular dementia. http://www.uptodate.com/home/index.html. Accessed March 12, 2009.
  5. Dementia. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/sec16/ch213/ch213c.html. Accessed March 14, 2009.
  6. Aricept (prescribing information). Woodcliff Lake, N.J.: Eisai Inc.; 2006. http://www.aricept.com/images/AriceptComboFullPINovember02006.pdf. Accessed March 12, 2009.
  7. Namenda (prescribing information). St. Louis, Mo.: Forrest Pharmaceuticals; 2007. http://www.frx.com/pi/namenda_pi.pdf. Accessed March 12, 2009.
  8. Aminoff MJ, et al. Disorders of cognitive function. In: Aminoff MJ, et al. Clinical Neurology. 6th ed. New York, N.Y.: McGraw-Hill Medical; 2005. http://www.accessmedicine.com/content.aspx?aID=2079000. Accessed March 11, 2009.
  9. Wright CB. Treatment and prevention of vascular dementia. http://www.uptodate.com/home/index.html. Accessed March 12, 2009.

DS00934

May 1, 2009

© 1998-2009 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Reliable tools for healthier lives," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

Print Share Reprints

Text Size: smaller largerlarger