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Definition

By Mayo Clinic staff

Vasculitis is an inflammation of your blood vessels. Vasculitis causes changes in the walls of your blood vessels, including thickening, weakening, narrowing and scarring.

There are many types of vasculitis. Some forms last only a short time (acute) while others are long lasting (chronic). Vasculitis, which is also known as angiitis and arteritis, can be so severe that the tissues and organs supplied by the affected vessels don't get enough blood. This shortage of blood can result in organ and tissue damage, even death.

Vasculitis can affect anyone, though some types of vasculitis are more common among certain groups. Some forms of vasculitis improve on their own, but others require treatment — often including taking medications for an extended period of time.

References
  1. What is vasculitis? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/vas/. Accessed Sept. 9, 2011.
  2. Sharma P, et al. Systemic vasculitis. American Family Physician. 2011;83:556.
  3. Langford CA. Vasculitis. Journal of Allergy and Clinical Immunology. 2010;125:S216.
  4. Langford CA, et al. The vasculitis syndromes. In: Fauci AS, et al. Harrison's Principles of Internal Medicine. 18th ed. New York, N.Y.: The McGraw Hill Companies; 2012. http://www.accessmedicine.com/content.aspx?aID=9138083. Accessed Sept. 9, 2011.
  5. Miller A, et al. An approach to the diagnosis and management of systemic vasculitis. Clinical and Experimental Immunology. 2010;160:143.
  6. Rituxan (prescribing information). San Francisco, Calif.: Genentech; 2011. http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/103705s5344lbl.pdf. Accessed Sept. 19, 2011.
  7. Chang-Miller A (expert opinion). Mayo Clinic, Rochester, Minn. Sept. 19, 2011.
  8. Falk RJ, et al. Granulomatosis with polyangiitis (Wegener's): An alternative name for Wegener's granulomatosis. Arthritis and Rheumatism. 2011;63:863.
DS00513 Oct. 8, 2011

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