• image.alt
  • With Mayo Clinic emeritus hypertension specialist

    Sheldon G. Sheps, M.D.

    read biography

Mayo Clinic Health Manager

Get free personalized health guidance for you and your family.

Get Started

Free

E-Newsletter

Subscribe to receive the latest updates on health topics. About our newsletters

  • Housecall
  • Alzheimer's caregiving
  • Living with cancer

Question

Vitamin D deficiency: Can it cause high blood pressure?

Can vitamin D deficiency cause high blood pressure?

Answer

from Sheldon G. Sheps, M.D.

It's long been known that vitamin D deficiency weakens bones. The role vitamin D may play in cardiovascular disease is less clear.

A number of recent studies suggest that vitamin D deficiency may be associated with cardiovascular disease and a higher risk of high blood pressure (hypertension). However, these results are preliminary and not consistent with various older studies on the topic. It's too early to say whether vitamin D deficiency causes high blood pressure — or whether vitamin D supplements may have any role in the treatment of high blood pressure.

Still, vitamin D remains an important nutrient for overall good health. The National Academy of Sciences currently recommends 200 international units (IU) of vitamin D a day for adults up to age 50. For adults older than age 50, the recommendation increases to 400 to 600 IU a day. However, many researchers now question whether these levels are adequate and assert that a daily intake of 800 to 1,000 IU would benefit many people. Generally, the upper limit for vitamin D is 2,000 IU a day.

If you're concerned that you're getting too little — or too much — vitamin D, contact your doctor. He or she may recommend a blood test to check the level of vitamin D in your blood.

Next question
Omega-6 fatty acids: Can they cause heart disease?
References
  1. Sheps SG (expert opinion). Mayo Clinic, Rochester, Minn. June 9, 2008.
  2. Dietary supplement fact sheet: Vitamin D. Office of Dietary Supplements. http://ods.od.nih.gov/factsheets/vitamind.asp. Accessed Sept. 5, 2008.
  3. Wang L, et al. Dietary intake of dairy products, calcium, and vitamin D and the risk of hypertension in middle-aged and older women. Hypertension. 2008;51(4):1073-1079.
  4. Judd SE, et al. Optimal vitamin D status attenuates the age-associated increase in systolic blood pressure in white Americans: Results from the third National Health and Nutrition Examination Survey. American Journal of Clinical Nutrition. 2008;87(1):136-141.
  5. Richart T, et al. Renal versus extrarenal activation of vitamin D in relation to atherosclerosis, arterial stiffening, and hypertension. American Journal of Hypertension. 2007;20(9):1007-1015.
  6. Forman JP, et al. Vitamin D intake and risk of incident hypertension: Results from three large prospective cohort studies. Hypertension. 2005;46(4):676-682.
  7. Wang TJ, et al. Vitamin D deficiency and risk of cardiovascular disease. Circulation. 2008;117(4):503-511.

AN01925

Oct. 22, 2008

© 1998-2009 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Reliable tools for healthier lives," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

Print Share Reprints

Text Size: smaller largerlarger