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  • With Mayo Clinic nutritionist

    Katherine Zeratsky, R.D., L.D.

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Mayo Clinic Health Manager

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Question

Vitamin D: How much is too much?

Is it possible to take too much vitamin D? I know vitamin D is important, but I wonder if too much is dangerous?

Answer

from Katherine Zeratsky, R.D., L.D.

Vitamin D is an essential nutrient for your entire body. Still, it's possible to have too much of a good thing.

Vitamin D has long been known to promote healthy bones. Some research suggests that vitamin D may also help prevent certain cancers, as well as diabetes, high blood pressure, multiple sclerosis and various other conditions.

Vitamin D is naturally present in some foods and is added to others. It is also available as a dietary supplement. The best food sources of vitamin D include salmon, mackerel, sardines, tuna and fortified milk. Cod liver oil also contains large amounts of vitamin D. Vitamin D is also produced by the body, triggered by sunlight on the skin.

Recent research suggests that many people may not be getting enough vitamin D. More exposure to sunlight can help, but this increases the risk of skin cancer and other skin problems. The National Academy of Sciences currently recommends 200 international units (IU) of vitamin D a day for children and adults up to age 50. This is about the amount of vitamin D in 3 ounces of tuna or 16 ounces of fortified milk. For adults older than age 50, the recommendation increases to 400 to 600 IU a day. If you're not getting enough vitamin D, your doctor may recommend vitamin D supplements. Still, moderation is important.

You're unlikely to get too much vitamin D from the food you eat, and prolonged sun exposure doesn't seem to cause vitamin D toxicity. Over time, however, megadoses of vitamin D supplements can cause nausea, vomiting, poor appetite, constipation, weakness and weight loss. More seriously, excessive doses of vitamin D can raise the level of calcium in your blood — which can cause confusion and changes in heart rhythm. Generally, the upper limit for vitamin D is 2,000 IU a day.

If you're concerned that you're getting too little — or too much — vitamin D, contact your doctor. He or she may recommend a blood test to check the level of vitamin D in your blood.

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References
  1. Dietary supplement fact sheet: Vitamin D. Office of Dietary Supplements. http://ods.od.nih.gov/factsheets/vitamind.asp. Accessed May 28, 2008.
  2. Hathcock J, et al. Risk assessment for vitamin D. American Journal of Clinical Nutrition. 2007;85(1):6-18.
  3. Holick M. Vitamin D deficiency. New England Journal of Medicine. 2007;357(3):266-281.
  4. Wagner CL, et al. Prevention of rickets and vitamin D deficiency in infants, children, and adolescents. Pediatrics. 2008;122(5):1142-1152.

AN01864

Dec. 19, 2008

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