Vitamin deficiency anemia


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Complications

By Mayo Clinic staff

Being deficient in vitamins increases your risk of many health problems:

  • Pregnancy complications. Pregnant women with folate deficiency may be more likely to experience miscarriage and deliver babies that are premature or are smaller than average. A developing fetus that doesn't get enough folate from its mother can develop birth defects of the brain and spinal cord. If you're thinking of becoming pregnant, ask your doctor whether you should consider taking folic acid supplements, so your body's stores of folate will be enough to support your baby.
  • Nervous system disorders. While vitamin B-12 is important for the production of red blood cells, it's also important for a healthy nervous system. Untreated, vitamin B-12 deficiency can lead to neurological problems, such as persistent tingling in your hands and feet. It can lead to mental confusion and forgetfulness, because vitamin B-12 is necessary for healthy brain function. Without treatment for vitamin B-12 deficiency, neurological complications can become permanent. Vitamin B-12 deficiency can cause these and other health problems before it leads to anemia.
  • Scurvy. Vitamin C deficiency can lead to scurvy. Signs and symptoms of this rare disease include bleeding under the skin and around the gums.
References
  1. Antony AC. Megaloblastic anemias. In: Hoffman R, et al. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2009. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-443-06715-0..X5001-8--TOP&isbn=978-0-443-06715-0&uniqId=230100505-56. Accessed Jan. 24, 2011.
  2. Pernicious anemia. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/prnanmia/prnanmia_all.html. Accessed Jan. 24, 2011.
  3. Zile M, et al. Vitamin C (ascorbic acid). In: Kliegman RM. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/208746819-6/0/1608/0.html. Accessed Jan. 27, 2011.
  4. Mason JB. Vitamins, trace minerals and other micronutrients. In: Goldman L, et al. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/das/book/body/191371208-2/0/1492/0.html#. Accessed Jan. 27, 2011.
  5. Dietary reference intakes (DRIs): Recommended intakes for individuals, vitamins. Institute of Medicine. http://iom.edu/en/Global/News%20Announcements/~/media/Files/Activity%20Files/Nutrition/DRIs/DRISummaryListing2.ashx. Accessed Jan. 28, 2011.
  6. USDA National Nutrient Database for Standard Reference, Release 23. U.S. Department of Agriculture. http://www.nal.usda.gov/fnic/foodcomp/search. Accessed Jan. 28, 2011.
DS00325 March 4, 2011

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