• image.alt
  • With Mayo Clinic cardiologist

    Thomas Behrenbeck, M.D., Ph.D.

    read biography

Free

E-Newsletters

Subscribe to receive the latest updates on health topics. About our newsletters

  • Housecall
  • Alzheimer's caregiving
  • Living with cancer

Question

VLDL cholesterol: Is it harmful?

What is VLDL cholesterol? Can it be harmful?

Answer

from Thomas Behrenbeck, M.D., Ph.D.

Very-low-density lipoprotein (VLDL) cholesterol is a type of lipoprotein. Although you may hear about VLDL, your VLDL level usually isn't reported to you as a part of a routine cholesterol test.

There are several types of cholesterol, each made up of lipoproteins and fats. Each type of lipoprotein contains a mixture of cholesterol, protein and a type of fat (triglyceride), but in varying amounts.

Of the lipoprotein types, VLDL contains the highest amount of triglyceride. Because it contains a high level of triglyceride, having a high VLDL level means you may have an increased risk of coronary artery disease, which can lead to a heart attack or stroke.

There's no simple, direct way to measure VLDL cholesterol, which is why it's normally not mentioned during a routine cholesterol screening. VLDL cholesterol is usually estimated as a percentage of your triglyceride value. A normal VLDL cholesterol level is between 5 and 40 milligrams per deciliter.

Next question
Arcus senilis: A sign of high cholesterol?
References
  1. VLDL. Lab tests online. http://www.labtestsonline.org/understanding/analytes/vldl/glance.html. Accessed March 2, 2010.
  2. Ren J, et al. Long term coronary heart disease risk associated with very-low-density lipoprotein cholesterol in Chinese: The result of a 15-year Chinese multi-provincial cohort study (CMCS). Atherosclerosis. In press. Accessed March 2, 2010.
  3. Adult treatment panel III executive summary. National Cholesterol Education Program. http://www.nhlbi.nih.gov/guidelines/cholesterol/atp3xsum.pdf. Accessed March 2, 2010.
AN01335 April 22, 2010

© 1998-2012 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

Print Share Reprints

Advertisement


Text Size: smaller largerlarger