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  • With Mayo Clinic emeritus hypertension specialist

    Sheldon G. Sheps, M.D.

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Question

Warfarin diet: What foods should I avoid?

Can you tell me what I should eat while I am taking warfarin (Coumadin)? What foods should I avoid?

Answer

from Sheldon G. Sheps, M.D.

Warfarin is a blood-thinning medication that helps treat and prevent blood clots. There is no specific warfarin (Coumadin) diet. However, certain foods and beverages can make it so warfarin doesn't effectively prevent blood clots. It's important to pay attention to what you eat while taking warfarin.

One nutrient that can lessen warfarin's effectiveness is vitamin K. It's important to be consistent in how much vitamin K you get daily. The average daily allowance of vitamin K for adult men is 120 micrograms (mcg). For adult women, it's 90 mcg. While eating small amounts of foods that are rich in vitamin K shouldn't cause a problem, avoid eating or drinking large amounts of:

  • Kale
  • Spinach
  • Brussels sprouts
  • Parsley
  • Collard greens
  • Mustard greens
  • Chard
  • Green tea

Certain drinks can increase the effect of warfarin, leading to bleeding problems. Avoid or drink only small amounts of these drinks when taking warfarin:

  • Cranberry juice
  • Alcohol

Talk to your doctor before making any major changes in your diet and before starting any over-the-counter medications, vitamins or herbal supplements. If you are unable to eat for several days or have ongoing stomach upset, diarrhea or fever, consult your doctor. These signs and symptoms may mean you need a different dose of warfarin.

Next question
Warfarin: Any harm in long-term use?
References
  1. deAssis MC, et al. Improved oral anticoagulation after a dietary vitamin K-guided strategy: A randomized controlled trial. Circulation. 2009;120:1115.
  2. Nutescu EA, et al. Warfarin and its interactions with foods, herbs and other dietary supplements. Expert Opinions on Drug Safety. 2006;5:433.
  3. Ford SK, et al. Vitamin K supplementation to decrease variability of international normalized ratio in patients on vitamin K antagonists: A literature review. Current Opinion in Hematology. 2008;15:504.
  4. Valentine KA, et al. Outpatient management of oral anticoagulation. http://www.uptodate.com/index. Accessed June 14, 2012.
  5. Ansell J, et al. Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th edition). Chest. 2008;130:160S.
  6. Coumadin and vitamin K. National Institutes of Health. http://www.cc.nih.gov/ccc/patient_education/drug_nutrient/coumadin1.pdf. Accessed June 14, 2012.
  7. Warfarin natural product and drug interactions. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed June 14, 2012.
AN00455 Aug. 7, 2012

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