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Complications
By Mayo Clinic staffBesides your upper and lower respiratory tracts, Wegener's granulomatosis may affect other organs, including your skin, eyes, ears, kidneys, spinal cord and heart. Complications may include:
- Hearing loss. Inflammation of granulated tissue in the middle ear can lead to hearing loss.
- Skin scarring. Sores may develop and may lead to severe scarring.
- Heart attack. Wegener's granulomatosis can affect the arteries of your heart, resulting in chest pain or heart attack.
- Kidney (renal) damage. As Wegener's granulomatosis progresses, it's likely to affect your kidneys. It can lead to glomerulonephritis, a type of kidney disease that hampers your kidneys' ability to remove waste and excess fluid from your body, leading to a buildup of waste products in your bloodstream (uremia). Kidney failure is a leading cause of death from Wegener's granulomatosis.
