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Symptoms
By Mayo Clinic staffSigns and symptoms of Wegener's granulomatosis symptoms may develop suddenly or gradually.
The first Wegener's granulomatosis symptoms usually involve your respiratory tract. However, the condition often worsens rapidly, affecting blood vessels and the organs they supply. Signs and symptoms may include:
- Constantly runny nose
- Nosebleeds
- Sinus pain and inflammation (sinusitis)
- Ear infections
- Cough
- Coughing up blood
- Shortness of breath
- General ill feeling (malaise)
- Appetite loss
- Joint aches and swelling
- Skin sores
- Eye redness, burning or pain
- Double or decreased vision
- Fever
- Weakness and fatigue, possibly associated with low red blood cell count (anemia)
For some people, the disease limits itself to the respiratory tract and doesn't involve the kidneys. Kidney involvement usually doesn't cause symptoms early in the course of the disease, and may be detected only by blood and urine tests. However, in time kidney failure with its associated anemia occurs.
When to see a doctor
See your doctor if you have a persistently runny nose that doesn't respond to over-the-counter (OTC) cold medicines, especially if it's accompanied by nosebleeds and pus-like material, coughing up blood, or other possible signs and symptoms of Wegener's granulomatosis. Because the disease can progress quickly, early diagnosis is critical to receiving effective treatment.
