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Risk factors

By Mayo Clinic staff

Your overall risk of getting West Nile virus depends on these factors:

  • Time of year. The majority of cases in the United States have occurred between the months of July and September.
  • Geographic region. West Nile virus has been reported in most of the United States, but Midwestern and Southern states have recently had the highest incidence rates.
  • Time spent outside. If you work or spend time outdoors, you have a greater chance of being bitten by an infected mosquito.

Risk of serious infection
Even if you're infected, your risk of developing a serious West Nile virus-related illness is extremely small — less than 1 percent of people who are infected become severely ill. And most people who do become sick recover fully. You're more likely to develop a severe or fatal infection based on:

  • Age. Adults older than age 50 are at higher risk of infection.
  • Health. Those who have a weakened immune system, such as after receiving an organ transplant with anti-rejection medication, are at greater risk of infection.
References
  1. West Nile virus: Questions and answers. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dvbid/westnile/qa/symptoms.htm. Accessed Sept. 5, 2012.
  2. West Nile virus: Fact sheet. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dvbid/westnile/wnv_factSheet.htm. Accessed Sept. 5, 2012.
  3. Petersen LR. Clinical manifestations and diagnosis of West Nile virus infection. http://www.uptodate.com/ index. Accessed Sept. 5, 2012.
  4. Ferri FF. Ferri's Clinical Advisor 2013: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2012. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-0-323-08373-7..00002-9&isbn=978-0-323-08373-7&about=true&uniqId=343863096-23. Accessed Sept. 6, 2012.
  5. West Nile virus. National Institute of Allergy and Infectious Diseases. http://www.niaid.nih.gov/topics/westnile/understanding/pages/what.aspx. Sept. 6, 2012.
  6. Centers for Disease Control and Prevention, et al. West Nile virus and other arborviral diseases — United States, 2011. MMWR. 2012;61:510. http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6127a3.htm?s_cid=mm6127a3_w. Accessed Sept. 5, 2012.
  7. Petersen LR. Treatment and prevention of West Nile virus infection. http://www.uptodate.com/ index. Accessed Sept. 5, 2012.
  8. Updated information regarding insect repellants. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dvbid/westnile/RepellentUpdates.htm. Accessed Sept. 7, 2012.
  9. Anderson CF (expert opinion). Mayo Clinic, Rochester, Minn. Sept. 10, 2012.
  10. Mahoney KR (expert opinion). Food and Drug Administration, Rockville, Md. Jan. 10, 2011.
DS00438 Dec. 18, 2012

© 1998-2013 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

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