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Risk factors

By Mayo Clinic staff

Factors that may increase your risk of macular degeneration include:

  • Age. Your risk of macular degeneration increases as you age, especially after age 50. Macular degeneration is most common in people older than 65.
  • Family history of macular degeneration. If someone in your family had macular degeneration, you're more likely to develop macular degeneration.
  • Race. Macular degeneration is more common in whites (Caucasians) than it is in other races.
  • Smoking. Smoking cigarettes increases your risk of macular degeneration.
  • Obesity. Being severely overweight increases the chance that early or intermediate macular degeneration will progress to the more severe form of the disease.
  • Diet. A diet that includes few fruits and vegetables may increase the risk of macular degeneration.
  • High blood pressure. Diseases that affect the circulatory system, such as high blood pressure or high cholesterol, may increase the risk of macular degeneration.
  • Inflammation. Your immune system can cause swelling of your body tissues, which may increase the risk of macular degeneration.
  • Cardiovascular disease. If you have had diseases that affected your heart and blood vessels (cardiovascular disease), you may be at higher risk of macular degeneration.
References
  1. Facts about age-related macular degeneration. National Eye Institute. http://www.nei.nih.gov/health/maculardegen/armd_facts.asp. Accessed Sept. 28, 2012.
  2. What is age-related macular degeneration? American Academy of Ophthalmology. http://www.geteyesmart.org/eyesmart/diseases/amd.cfm. Accessed Sept. 28, 2012.
  3. Arroyo JG. Age-related macular degeneration: Epidemiology, etiology, and diagnosis. http://www.uptodate.com/index. Accessed Aug. 29, 2012.
  4. Macular degeneration symptoms. American Academy of Ophthalmology http://www.geteyesmart.org/eyesmart/diseases/amd-symptoms.cfm. Accessed Sept. 27, 2012.
  5. Yanoff M, ed., et al. Ophthalmology. 3rd ed. Edinburgh, U.K.: Mosby Elsevier; 2009. http://www.mdconsult.com/das/book/body/212799885-2/0/1869/0.html. Accessed Sept. 28, 2012.
  6. Who is at risk for macular degeneration? American Academy of Ophthalmology. http://www.geteyesmart.org/eyesmart/diseases/amd-risk.cfm. Accessed Sept. 28, 2012.
  7. Arroyo JG. Age-related macular degeneration: Treatment and prevention. http://www.uptodate.com/index. Accessed Sept. 28, 2012.
  8. Macular degeneration diagnosis. American Academy of Ophthalmology. http://www.geteyesmart.org/eyesmart/diseases/amd-diagnosis.cfm. Accessed Sept. 28, 2012.
  9. Macular degeneration treatment. American Academy of Ophthalmology. http://www.geteyesmart.org/eyesmart/diseases/amd-treatment.cfm. Accessed Sept. 28, 2012.
  10. Macular degeneration and low vision. American Academy of Ophthalmology. http://www.geteyesmart.org/eyesmart/diseases/amd-low-vision.cfm. Accessed Sept. 27, 2012.
  11. Low vision aids and low vision rehabilitation. American Academy of Ophthalmology. http://www.geteyesmart.org/eyesmart/diseases/low-vision-aids-rehabilitation.cfm. Accessed Sept. 28, 2012.
  12. Robertson DM (expert opinion). Mayo Clinic, Rochester, Minn. Oct. 15, 2012.
  13. Hughes DF. Charles Bonnet syndrome: A literature review into diagnostic criteria, treatment and implications for nursing practice. Journal of Psychiatric and Mental Health Nursing. Accessed Sept. 28, 2012.
  14. Visudyne (prescribing information). Vancouver, Canada: QLT Inc.; 2010. http://www.visudyne.com/pub/patient/en-us/common/prescribing-information.aspx. Accessed Oct. 15, 2012.
DS01086 Dec. 1, 2012

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