Mayo Clinic Health Manager
Get free personalized health guidance for you and your family.
Get Started
About our e-newsletters
- Free e-newsletters
- Mayo Clinic expertise
- We do not share your e-mail address
Housecall, our weekly general-interest e-newsletter, keeps you up to date on a wide variety of health topics with timely, reliable, practical information, recipes, blogs, questions and answers with Mayo Clinic experts and more. Our biweekly topic-specific e-newsletters also include blogs, questions and answers with Mayo Clinic experts, and other useful information that will help you manage your health.
Housecall Archives
Mayo Clinic Housecall
Stay up to date on the latest health information.
What you get
- Free weekly e-newsletter
- Mayo Clinic expertise
- Recipes, tools and other helpful information
- We do not share your e-mail address
Symptoms
By Mayo Clinic staffMany common signs and symptoms of Whipple's disease involve your gastrointestinal system and include:
- Diarrhea
- Abdominal cramping and pain, which tends to worsen after meals in some cases
- Weight loss, associated with the malabsorption of nutrients
Other frequent signs and symptoms associated with Whipple's disease include:
- Inflamed joints, particularly your ankles, knees and wrists
- Fatigue
- Weakness
- Anemia
Less common signs and symptoms are:
- Low-grade fever
- Cough
- Enlarged lymph nodes
- Difficulty walking
- Skin darkening (hyperpigmentation) in areas exposed to the sun, and in scars
- Visual impairment, including lack of control of eye movements
- Discomfort while breathing, due to inflammation of the membranes lining your lungs (pleurisy)
- Heart murmurs
- Enlarged spleen
- Seizures
- Confusion
- Memory loss
Symptoms tend to develop slowly over a period of many years in most people with the disease.
