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Definition

By Mayo Clinic staff

Whooping cough (pertussis) is a highly contagious respiratory tract infection. In many people, it's marked by a severe hacking cough followed by a high-pitched intake of breath that sounds like "whoop."

Before the vaccine was developed, whooping cough was considered a childhood disease. Now whooping cough primarily affects children too young to have completed the full course of vaccinations and teenagers and adults whose immunity has faded.

Deaths associated with whooping cough are rare but most commonly occur in infants. That's why it's so important for pregnant women — and other people who will have close contact with an infant — to be vaccinated against whooping cough.

References
  1. Pertussis (whooping cough): What you need to know. Centers for Disease Control and Prevention. http://www.cdc.gov/Features/Pertussis. Accessed Dec. 6, 2011.
  2. Hewlett EL. Whooping cough and other bordetella infections. In: Goldman L, et al. Cecil Medicine. 24th ed. Philadelphia, Pa.: Saunders Elsevier; 2011. http://www.mdconsult.com/das/book/body/191371208-2/0/1492/0.html#. Accessed Dec. 6, 2011.
  3. Long SS. Pertussis. In: Kliegman RM, et al. Nelson Textbook of Pediatrics. 19th ed. Philadelphia, Pa.: Saunders Elsevier; 2011. http://www.mdconsult.com/das/book/body/208746819-6/0/1608/0.html. Accessed Dec. 6, 2011.
  4. Centers for Disease Control and Prevention. Updated recommendations for use of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine (Tdap) in pregnant women and persons who have or anticipate having close contact with an infant <12 months. 2011;60:1424. http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6041a4.htm?s_cid=mm6041a4_e%0d%0a. Accessed Dec. 6, 2011.
  5. Yeh S, et al. Clinical features and diagnosis of Bordetella pertussis infection in infants and children. http://www.uptodate.com/home/index.html. Accessed Dec. 6, 2011.
  6. Byrd EM, et al. Clinical features and diagnosis of Bordetella pertussis infection in adolescents and adults. http://www.uptodate.com/home/index.html. Accessed Dec. 6, 2011.
  7. Yeh S. Treatment and prevention of Bordetella pertussis infection in infants and children. http://www.uptodate.com/home/index.html. Accessed Dec. 6, 2011.
  8. Byrd EM, et al. Treatment and prevention of Bordetella pertussis infection in adolescents and adults. http://www.uptodate.com/home/index.html. Accessed Dec. 6, 2011.
  9. Recommended immunization schedule for adults aged 19 years and older — United States, 2013. Centers for Disease Control and Prevention http://www.cdc.gov/vaccines/schedules/hcp/child-adolescent.html. Accessed Feb. 19, 2013.
  10. Recommended immunization schedule for persons aged 0 through 18 years — United States, 2013. Centers for Disease Control and Prevention http://www.cdc.gov/vaccines/schedules/hcp/child-adolescent.html. Accessed Feb. 19, 2013.
DS00445 March 19, 2013

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