Prevention
By Mayo Clinic staffThe best way to prevent whooping cough is with the pertussis vaccine, which doctors often give in combination with vaccines against two other serious diseases — diphtheria and tetanus. Doctors recommend beginning vaccination during infancy.
The vaccine consists of a series of five injections, typically given to children at these ages:
- 2 months
- 4 months
- 6 months
- 15 to 18 months
- 4 to 6 years
Vaccine side effects
Side effects of the vaccine may include fever, crankiness or soreness at the site of the injection. In rare cases, severe side effects may occur, including:
- Persistent crying, lasting more than three hours
- High fever
- Seizures, shock or coma
Booster shots
- Adolescents. Because immunity from the pertussis vaccine tends to wane by age 11, doctors recommend a booster shot at that age to protect against whooping cough (pertussis), diphtheria and tetanus.
- Adults. Some varieties of the every-10-year tetanus and diphtheria vaccine also include protection against whooping cough (pertussis). In addition to protecting you against whooping cough, this vaccine will also reduce the risk of your transmitting whooping cough to infants.
- Pregnant women. The Centers for Disease Control and Prevention now recommends that pregnant women receive the pertussis vaccine between 27 weeks and 36 weeks of gestation. This may also give some protection to the infant during the first few months of life.
- Pertussis (whooping cough): What you need to know. Centers for Disease Control and Prevention. http://www.cdc.gov/Features/Pertussis. Accessed Dec. 6, 2011.
- Hewlett EL. Whooping cough and other bordetella infections. In: Goldman L, et al. Cecil Medicine. 24th ed. Philadelphia, Pa.: Saunders Elsevier; 2011. http://www.mdconsult.com/das/book/body/191371208-2/0/1492/0.html#. Accessed Dec. 6, 2011.
- Long SS. Pertussis. In: Kliegman RM, et al. Nelson Textbook of Pediatrics. 19th ed. Philadelphia, Pa.: Saunders Elsevier; 2011. http://www.mdconsult.com/das/book/body/208746819-6/0/1608/0.html. Accessed Dec. 6, 2011.
- Centers for Disease Control and Prevention. Updated recommendations for use of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine (Tdap) in pregnant women and persons who have or anticipate having close contact with an infant <12 months. 2011;60:1424. http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6041a4.htm?s_cid=mm6041a4_e%0d%0a. Accessed Dec. 6, 2011.
- Yeh S, et al. Clinical features and diagnosis of Bordetella pertussis infection in infants and children. http://www.uptodate.com/home/index.html. Accessed Dec. 6, 2011.
- Byrd EM, et al. Clinical features and diagnosis of Bordetella pertussis infection in adolescents and adults. http://www.uptodate.com/home/index.html. Accessed Dec. 6, 2011.
- Yeh S. Treatment and prevention of Bordetella pertussis infection in infants and children. http://www.uptodate.com/home/index.html. Accessed Dec. 6, 2011.
- Byrd EM, et al. Treatment and prevention of Bordetella pertussis infection in adolescents and adults. http://www.uptodate.com/home/index.html. Accessed Dec. 6, 2011.
- Recommended immunization schedule for adults aged 19 years and older — United States, 2013. Centers for Disease Control and Prevention http://www.cdc.gov/vaccines/schedules/hcp/child-adolescent.html. Accessed Feb. 19, 2013.
- Recommended immunization schedule for persons aged 0 through 18 years — United States, 2013. Centers for Disease Control and Prevention http://www.cdc.gov/vaccines/schedules/hcp/child-adolescent.html. Accessed Feb. 19, 2013.


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