Mayo Clinic Health Manager
Get free personalized health guidance for you and your family.
Get StartedSymptoms
By Mayo Clinic staffWrinkles are the lines and creases that form in your skin as you age. Some wrinkles can become deep crevices or furrows and may be especially noticeable around your eyes, mouth and neck.
When to see a doctor
If you're concerned about the appearance of your skin, see your dermatologist. He or she can help you create a personalized skin-care plan by assessing your skin type and evaluating your skin's condition. A dermatologist can also recommend medical wrinkle treatments.
- McCullough JL, et al. Prevention and treatment of skin aging. Annals of the New York Academy of Sciences. 2006;1067:323.
- Renova (tretinoin cream). U.S. Food and Drug Administration. http://www.fda.gov/cder/foi/label/2002/21108s1lbl.pdf. Accessed Nov. 25, 2008.
- Rabe JH, et al. Photoaging: Mechanisms and repair. Journal of the American Academy of Dermatology. 2006;55:1.
- Soft tissue fillers. American Academy of Dermatology. http://www.aad.org/public/Publications/pamphlets/SoftTissueFillers.htm. Accessed Nov. 25, 2008.
- Kafi R, et al. Improvement of naturally aged skin with vitamin A (retinol). Archives of Dermatology. 2007;143:606.
- Facial skin rejuvenation. American Academy of Dermatology. http://www.aad.org/public/publications/pamphlets/cosmetic_facial.html. Accessed Nov. 25, 2008.
- Helfrich YR, et al. Overview of skin aging and photoaging. Dermatology Nursing. 2008;20:177.
- Mature skin. American Academy of Dermatology. http://www.aad.org/public/Publications/pamphlets/MatureSkin.htm. Accessed Nov. 25, 2008.
- Baumann L. Cosmetics and skin care in dermatology. In: Wolff K, et al. Fitzpatrick's Dermatology in General Medicine. 7th ed. New York, N.Y.: The McGraw-Hill Companies; 2008. http://accessmedicine.com/content.aspx?aID=3007166&searchStr=xerosis. Accessed Nov. 25, 2008.
- Freiman A, et al. Cutaneous effects of smoking. Journal of Cutaneous Medicine and Surgery. 2004;8:415.
- Physician's guide to cosmetic surgery: Facial surgery and skin care surgical procedures. American Society of Plastic Surgeons. http://www.plasticsurgery.org/medical_professionals/publications/Physicians-Guide-to-Cosmetic-Surgery-Facial-Surgery.cfm#. Accessed Nov. 25, 2008.
- Rados C. Science meets beauty: Using medicine to improve appearances. FDA Consumer Magazine. http://www.fda.gov/fdac/features/2004/204_beauty.html. Accessed Aug. 20, 2008.
- Just M, et al. Effect of smoking on skin elastic fibres: Morphometric and immunohistochemical analysis. British Journal of Dermatology. 2007;156:85.