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Symptoms
By Mayo Clinic staffZollinger-Ellison syndrome causes signs and symptoms similar to those of a peptic ulcer. These may include:
- Burning, aching, gnawing or discomfort in your upper abdomen
- Diarrhea
- Heartburn
- Nausea and vomiting
- Weakness
- Bleeding in your digestive tract
- Unintended weight loss
When to see a doctor
See your doctor if you have a persistent burning, aching or gnawing pain in your upper abdomen, especially if you've also been experiencing nausea, vomiting and diarrhea.
Don't use over-the-counter acid-reducing medications such as omeprazole (Prilosec), cimetidine (Tagamet), famotidine (Pepcid) or ranitidine (Zantac) for long periods of time without your doctor's knowledge. These medications may mask your symptoms, which could delay your diagnosis. If you have Zollinger-Ellison syndrome, early detection and treatment are important.
