Mesothelioma

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Definition

By Mayo Clinic staff

Living with cancer newsletter

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Malignant mesothelioma (me-zoe-thee-lee-OH-muh) is a rare cancer that occurs in the thin layer of tissue that covers the majority of your internal organs (mesothelium).

Doctors divide mesothelioma into different types based on what part of the mesothelium is affected. Mesothelioma most often affects the tissue that surrounds the lungs (pleura). This type is called pleural malignant mesothelioma. Other, rarer types of mesothelioma affect tissue in the abdomen, around the heart and around the testicles.

Mesothelioma is an aggressive and deadly form of cancer. Mesothelioma treatments are available, but for many people with mesothelioma, a cure is not possible. Instead, treatment for mesothelioma is often focused on keeping you as comfortable as possible.

Symptoms
References
  1. Malignant pleural mesothelioma. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/PDF/mpm.pdf. Accessed June 28, 2010.
  2. Sovak MA, et al. Tumors of the pleura and mediastinum. In: Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone; 2007:1367.
  3. Broaddus VC, et al. Tumors of the pleura. In: Murray and Naedel's Textbook of Respiratory Medicine. 5th ed. Philadelphia, Pa.: Saunders; 2010. http://www.mdconsult.com/book/player/book.do?method=display&type=aboutPage&decorator=header&eid=4-u1.0-B978-1-4160-4710-0..C2009-0-37805-8--TOP&isbn=978-1-4160-4710-0&uniq=207463617#lpState=open&lpTab=contentsTab&content=4-u1.0-B978-1-4160-4710-0..C2009-0-37805-8--TOP%3Bfrom%3Dcontent%3Bisbn%3D978-1-4160-4710-0%3Btype%3DbookHome. Accessed June 28, 2010.
  4. Mesothelioma: Questions and answers. National Cancer Institute. http://www.cancer.gov/cancertopics/factsheet/sites-types/mesothelioma. Accessed June 28, 2010.
  5. Alexander HR. Malignant peritoneal mesothelioma. http://www.uptodate.com/home/index.html. Accessed June 29, 2010.
  6. Frias-Kletecka MC, et al. Mesothelioma of the tunica vaginalis. The Journal of Urology. 2007;178:1489.
  7. Malignant mesothelioma treatment (PDQ). National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/malignantmesothelioma/patient/allpages. Accessed June 28, 2010.
  8. Frequently asked questions about cancer, simian virus 40 (SV40) and polio vaccine. U.S. Centers for Disease Control and Prevention. http://www.cdc.gov/vaccinesafety/updates/archive/polio_and_cancer.htm. Accessed June 29, 2010.
  9. Thorium: ToxFAQs. Agency for Toxic Substances & Disease Registry. http://www.atsdr.cdc.gov/toxfaqs/tf.asp?id=659&tid=121. Accessed June 29, 2010.
  10. Schartzstein RM, et al. Dyspnea. In: Murray and Naedel's Textbook of Respiratory Medicine. 5th ed. Philadelphia, Pa.: Saunders; 2010. http://www.mdconsult.com/book/player/book.do?method=display&type=aboutPage&decorator=header&eid=4-u1.0-B978-1-4160-4710-0..C2009-0-37805-8--TOP&isbn=978-1-4160-4710-0&uniq=207463617#lpState=open&lpTab=contentsTab&content=4-u1.0-B978-1-4160-4710-0..C2009-0-37805-8--TOP%3Bfrom%3Dcontent%3Bisbn%3D978-1-4160-4710-0%3Btype%3DbookHome. Accessed June 28, 2010.
  11. Bausewein C, et al. Non-pharmacological intervention for breathlessness in advanced stages of malignant and non-malignant diseases. Cochrane Database of Systematic Reviews. 2009;CD005623.
  12. Asbestos: Basic information. U.S. Environmental Protection Agency. http://www.epa.gov/asbestos/pubs/help.html. Accessed June 29, 2010.
DS00779 Aug. 7, 2010

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