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Rheumatoid arthritis: Can it affect the eyes?
By Mayo Clinic staffOriginal Article: http://www.mayoclinic.com/health/rheumatoid-arthritis/AN01485

- With Mayo Clinic rheumatologist
April Chang-Miller, M.D.
read biographyclose windowBiography of
April Chang-Miller, M.D.
April Chang-Miller, M.D.
Dr. April Chang-Miller is board certified in internal medicine and rheumatology and is a consultant in the Division of Rheumatology at Mayo Clinic in Arizona.
Dr. Chang-Miller's primary field is rheumatology with special interests in inflammatory joint diseases called seronegative spondyloarthropathies, such as ankylosing spondylitis and psoriatic arthritis. She also cares for patients with rheumatoid arthritis and polymyalgia rheumatica.
The New York City native is a graduate of the Yale School of Medicine. Dr. Chang-Miller joined the Mayo Clinic staff in Rochester, Minn., in 1991, and in 2002 she relocated to Mayo Clinic in Arizona. She is a fellow in the American College of Rheumatology and has been on the board of directors of the Arthritis Foundation North Central Chapter.
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Question
Rheumatoid arthritis: Can it affect the eyes?
Can rheumatoid arthritis affect the eyes?
Answer
from April Chang-Miller, M.D.
Rheumatoid arthritis is primarily a joint disease. However, rheumatoid arthritis occasionally affects other parts of the body — including the eyes. Eye conditions associated with rheumatoid arthritis may include:
- Dry eyes. Generally, preservative-free artificial tears can ease the discomfort of dry eyes. It's important to note that dry eyes also can be a symptom of Sjogren's syndrome — an autoimmune disorder that's often associated with rheumatoid arthritis.
- Inflammation of the interior of the eye (uveitis). Uveitis may cause eye redness and pain, light sensitivity and blurred vision.
- Inflammation of the membrane covering the white part of the eye (episcleritis). Episcleritis may cause sudden eye discomfort or redness.
- Inflammation of the white part of the eye (scleritis). Scleritis is usually characterized by constant, severe eye pain and tenderness. Sometimes the white of the eye takes on the appearance of a deep violet color — deeper than the eye redness typically seen with episcleritis.
- Glaucoma. Inflammation within the eye can affect the eye's drainage system, ultimately leading to glaucoma — a condition that can result in blindness. Depending on the type of glaucoma, signs and symptoms may include gradual vision loss, eye pain or blurred vision.
- Cataracts. Several factors may lead to clouding of the normally clear lens of the eye (cataracts), including inflammation within the eye and long-term use of corticosteroid medications often prescribed to treat rheumatoid arthritis. Signs and symptoms may include cloudy, blurred or dim vision.
If you have rheumatoid arthritis and experience eye pain, vision changes or other eye problems, consult an ophthalmologist for an evaluation. Also consult your rheumatologist. Early treatment can help prevent vision-threatening complications.
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- Rosenbaum JT. The eye and rheumatic diseases. In: Firestein GS, et al. Kelley's Textbook of Rheumatology. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2009. http://www.mdconsult.com/das/book/body/208746819-6/0/1807/0.html. Accessed Sept. 9, 2010.
- Hochberg MC, et al. Extra-articular features of rheumatoid arthritis and systemic involvement. In: Hochberg MC, et al. Rheumatology. 4th ed. Philadelphia, Pa.: Mosby Elsevier; 2008:778.
- Dana R. Ocular manifestations of rheumatoid arthritis. http://www.uptodate.com/home/index.html. Accessed Sept. 9, 2010.


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