Why it's done

Hormone therapy for prostate cancer is used to stop your body from producing the male hormone testosterone, which fuels the growth of prostate cancer cells.

Your doctor may recommend hormone therapy for prostate cancer as an option at different times and for different reasons during your cancer treatment.

Hormone therapy can be used:

  • In advanced (metastatic) prostate cancer, to shrink the cancer and slow the growth of tumors — which might relieve signs and symptoms
  • In prostate cancer that recurs after treatment
  • In locally advanced prostate cancer, to make external beam radiation therapy more effective
  • In those with a high risk of recurrence after initial treatment, to reduce that risk
April 26, 2016
References
  1. Wein AJ, et al., eds. Diagnosis and staging of prostate cancer. In: Campbell-Walsh Urology. 11th ed. Philadelphia, Pa.: Elsevier; 2016. http://www.clinicalkey.com. Accessed Jan. 25, 2016.
  2. Dawson NA. Overview of the treatment of disseminated prostate cancer. http://www.uptodate.com/home. Accessed Jan. 25, 2016.
  3. Niederhuber JE, et al., eds. Prostate cancer. In: Abeloff's Clinical Oncology. 5th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2014. http://www.clinicalkey.com. Accessed Jan. 26, 2016.
  4. Lee RJ, et al. Initial systemic therapy for castration sensitive prostate cancer. http://www.uptodate.com/home. Accessed Jan. 25, 2016.
  5. Roach M. Current trends for the use of androgen deprivation therapy in conjunction with radiotherapy for patients with unfavorable intermediate-risk, high-risk, localized, and locally advanced prostate cancer. Cancer. 2014;120:1620.
  6. Smith MR, et al. Side effects of androgen deprivation therapy. http://www.uptodate.com/home. Accessed Jan. 25, 2016.
  7. Dawson NA. Secondary endocrine therapies for castration resistant prostate cancer. http://www.uptodate.com/home. Accessed Jan. 25, 2016.
  8. Steele GS, et al. Radical inguinal orchiectomy for testicular germ cell cancers. http://www.uptodate.com/home. Accessed Jan. 25, 2016.